Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Black Lung Program, Miners' Colfax Medical Center, Raton, NM, USA.
COPD. 2020 Oct;17(5):509-514. doi: 10.1080/15412555.2020.1804847. Epub 2020 Aug 24.
Chronic obstructive pulmonary disease (COPD) is a significant cause of morbidity among miners. There is an increasing number of women in the mining industry and the differences in their risk for COPD compared to men miners are not understood. Our objective is to compare the odds for COPD between male and female miners. Using cross-sectional data from the ning ust in the nited tates (MiDUS) Cohort, that included New Mexico miners between 1989 and 2018, we compared the odds for airflow obstruction or chronic bronchitis between women and men. There were 299 women in this diverse cohort of 7,464 miners. Compared to men, female miners reported lower cumulative smoking but higher prevalence of current smoking. Multivariable analysis showed that women miners had significantly lower odds for having airflow obstruction (OR 0.40; 95% CI (0.26, 0.6)) and chronic bronchitis (OR 0.31, 95% CI (0.19, 0.53)) than men. Future studies need to determine whether this sex difference is explained by residual confounders or true biological difference.
慢性阻塞性肺疾病（COPD）是矿工发病的主要原因之一。越来越多的女性加入到采矿业，而女性矿工患 COPD 的风险与男性矿工相比存在差异，目前尚不清楚。本研究旨在比较男性和女性矿工患 COPD 的几率。我们使用了来自美国新墨西哥州矿业工人健康研究（MiDUS）队列的横断面数据，该研究纳入了 1989 年至 2018 年期间的矿工，比较了女性和男性矿工发生气流受限或慢性支气管炎的几率。在这个由 7464 名矿工组成的多样化队列中，有 299 名女性。与男性矿工相比，女性矿工报告的累积吸烟量较低，但当前吸烟率较高。多变量分析显示，女性矿工发生气流受限（OR 0.40；95%CI（0.26，0.6））和慢性支气管炎（OR 0.31，95%CI（0.19，0.53））的几率明显低于男性。未来的研究需要确定这种性别差异是由残余混杂因素还是真正的生物学差异解释。
