Department of Anesthesiology, Laveran Military Teaching Hospital, Marseille, France.
Department of Anesthesiology, Saint-Anne Military Teaching Hospital, Toulon, France.
Clin Neurol Neurosurg. 2020 Oct;197:106125. doi: 10.1016/j.clineuro.2020.106125. Epub 2020 Aug 2.
Pain after supratentorial craniotomy is common, 55 % to 80 % of patients experience moderate to severe pain in the first 48 h(1-7). The importance of intravenous dexamethasone as an adjuvant to local anaesthetics is increasingly applied(1-7), however its role in scalp nerve blocks with ropivacaine 0.75 % remains unexplored in post-operative analgesia. We analyzed 134 supratentorial craniotomies under general anaesthesia, 46 of which had preoperatively bilateral scalp nerve blocks with ropivacaine 0.75 %. The general anaesthesia was standardized and included 8 mg of intravenous dexamethasone at the induction. The postoperative pain was assessed using the numerical rating scale with patients in the post anaesthesia care unit and subsequently every 8 h in the neurosurgery unit until the 48th hour. A NRS value above 3 led to the administration of a rescue analgesic according to the defined protocol until an efficient analgesia was obtained. Postoperative pain was controlled in both groups, however the need for rescue analgesics in the scalp nerve blocks group was reduced by 40 % (39 % vs. 65 %; p = 0.006) compared to the control group. More than 60 % of the patients from the scalp nerve blocks group had an efficient analgesia without any rescue analgesic. Peroperatively the scalp nerve blocks group showed a decrease in opioid consumption and a better hemodynamic stability. No anesthetic or chirurgical complications related to the use of scalp blocks were observed. Scalp nerve blocks associated with intravenous dexamethasone are found to be a straightforward and efficient analgesic approach during supratentorial craniotomies.
颅脑手术后疼痛很常见,55%至 80%的患者在术后 48 小时内会经历中到重度疼痛(1-7)。静脉注射地塞米松作为局部麻醉剂的辅助药物的重要性日益增加(1-7),然而,其在 0.75%罗哌卡因头皮神经阻滞中的作用在术后镇痛中尚未得到探索。我们分析了 134 例全麻下颅脑手术,其中 46 例术前双侧头皮神经阻滞采用 0.75%罗哌卡因。全麻标准化,诱导时静脉给予 8mg 地塞米松。术后疼痛采用数字评分法在麻醉后监护室和神经外科病房进行评估,直至术后 48 小时,每 8 小时评估一次。NRS 值大于 3 时,根据既定方案给予解救性镇痛,直至获得有效的镇痛。两组患者术后疼痛均得到控制,但头皮神经阻滞组需要解救性镇痛的患者减少了 40%(39%比 65%;p=0.006)。头皮神经阻滞组超过 60%的患者无需解救性镇痛即可获得有效镇痛。术中头皮神经阻滞组阿片类药物用量减少,血流动力学更稳定。未观察到与头皮阻滞相关的麻醉或手术并发症。静脉注射地塞米松联合头皮神经阻滞是颅脑手术中一种简单有效的镇痛方法。