Jyotsana Nidhi, King Michael R
Department of Biomedical Engineering, Vanderbilt University, Nashville, TN USA.
Cell Mol Bioeng. 2020 Jun 29;13(4):285-291. doi: 10.1007/s12195-020-00630-3. eCollection 2020 Aug.
Millions of people are being infected with COVID-19 around the globe. Though the majority of them will recover, cancer patients remain at a higher risk to SARS-CoV-2 infection and its related severe outcomes. Understanding how viruses contribute to human cancers provides us with new opportunities for preventing or treating virus-associated cancers. However, a limited amount of research has been done to date in the context of how viral infections impact cancer at the cellular level and . Therefore, in light of the COVID-19 global infection, this review highlights the need for better understanding of the biology of viral infections in cancer patients, to enable novel therapies to co-target viral infections and cancer.
全球数以百万计的人感染了新冠病毒。尽管其中大多数人会康复,但癌症患者感染新冠病毒及其相关严重后果的风险仍然较高。了解病毒如何导致人类癌症为我们预防或治疗病毒相关癌症提供了新的机会。然而,迄今为止,在病毒感染如何在细胞水平上影响癌症这方面所做的研究有限。因此,鉴于新冠病毒的全球感染情况,本综述强调需要更好地了解癌症患者病毒感染的生物学特性,以便开发出能够同时针对病毒感染和癌症的新疗法。