Pharmacy Department, University Clinical Hospital 'Lozano Blesa', Zaragoza, Aragon, Spain.
Department of Microbiology, Preventive Medicine and Public Health, University of Zaragoza, Zaragoza, Aragon, Spain.
Eur J Hosp Pharm. 2020 Sep;27(5):306-309. doi: 10.1136/ejhpharm-2018-001593. Epub 2018 Nov 16.
In the process of determining if a drug is valuable enough to be included in a hospital's pharmacotherapeutic repertoire many factors should be taken into account. In order to develop a guide, the methodology of different appraisal working groups and similar methodological documents published by Health Technology Assessment agencies have been taken into account. We recommend that reports are structured with the following headings: Medication/Description/Authorised indication; Description of the disease; Pathology reference treatment; Evaluation of efficacy and safety (Bibliographic search, Quality assessment, Efficacy and safety results); Assessment of ethical, organisational, social and legal aspects; Strengths and limitations of available evidence; Pharmacoeconomic evaluation; and Key points. This guide to evaluate technologies may be used as a tool in decision-making scenarios related to health innovation. It could be used by hospital pharmacists and by clinicians, health system professionals and public services advisors.
在确定一种药物是否有足够的价值被纳入医院的药物治疗方案中时,需要考虑许多因素。为了制定指南,我们考虑了不同评估工作组的方法学和卫生技术评估机构发布的类似方法学文件。我们建议报告的结构采用以下标题:药物/描述/授权适应证;疾病描述;参考治疗的病理学;疗效和安全性评估(文献检索、质量评估、疗效和安全性结果);伦理、组织、社会和法律方面的评估;现有证据的优缺点;药物经济学评价;以及关键点。该技术评估指南可作为与卫生创新相关的决策场景中的工具使用。它可以由医院药剂师和临床医生、卫生系统专业人员和公共服务顾问使用。