Eberle J, Prior C, zur Nedden D, Jakse G
Klinik für Urologie, Universität Innsbruck, Osterreich.
Urologe A. 1988 Jan;27(1):54-7.
Malacoplakia is a granulomatous disease that most frequently involves the genitourinary tract. Because of the great variability of symptoms and lack of typical radiologic findings, this disease is usually not considered preoperatively. Generally of benign nature in the lower urinary tract, it leads to destruction and loss of renal function when affecting ureter and kidney. Progression of the latter can only be prevented by surgical intervention. Malacoplakia of the lower urinary tract requires long-term treatment with intracellularly active antibiotics in combination with drugs enhancing phagocytosis.
软斑病是一种肉芽肿性疾病,最常累及泌尿生殖道。由于症状差异极大且缺乏典型的影像学表现,这种疾病在术前通常不会被考虑。在下尿路一般为良性,但累及输尿管和肾脏时会导致肾功能破坏和丧失。只有通过手术干预才能阻止后者的进展。下尿路软斑病需要长期使用具有细胞内活性的抗生素联合增强吞噬作用的药物进行治疗。