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婴儿因经皮接触5%和7%的局部用米诺地尔而出现严重多毛症。

Severe hypertrichosis in infants due to transdermic exposure to 5% and 7% topical minoxidil.

作者信息

Rica Echevarría Itxaso, García Del Monte Javier, Delgado Rubio Alfonso, Arcangeli Fabio, Lotti Torello

机构信息

Pediatric Endocrinology Section, Cruces Hospital, CIBERDEM, CIBERER, Barakaldo, Spain.

Primary Care Pediatric Service, Monterrozas Health Center, Madrid, Spain.

出版信息

Dermatol Ther. 2020 Nov;33(6):e14230. doi: 10.1111/dth.14230. Epub 2020 Sep 21.

Abstract

We report three cases of severe hypertrichosis in healthy infants, who did not present any type of endocrinological pathology and whose parents used topical minoxidil for the treatment of their baldness. Any type of direct application or administration of the product was ruled out. Hypertrichosis is considered to have occurred through skin-to-skin contact with the parent, and even through fomites. Given the widespread use of topical minoxidil, it is likely that this etiology of childhood hypertrichosis is underdiagnosed and that it sometimes leads to minimal forms that go unnoticed.

摘要

我们报告了3例健康婴儿严重多毛症的病例,这些婴儿未出现任何类型的内分泌病理学情况,且其父母使用局部用米诺地尔治疗脱发。排除了该产品的任何直接涂抹或给药情况。多毛症被认为是通过与父母的皮肤接触,甚至通过污染物发生的。鉴于局部用米诺地尔的广泛使用,儿童多毛症的这种病因很可能未得到充分诊断,且有时会导致未被注意到的轻微症状。

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