Lynch Jeremy A
University of Illinois at Chicago, 4020 MBRB, 900 Ashland Ave., Chicago, IL 60607, USA.
Curr Opin Insect Sci. 2014 Jul;1:39-44. doi: 10.1016/j.cois.2014.05.003. Epub 2014 May 6.
Anterior-posterior (AP) patterning is an essential process that requires the generation of large amounts of positional information to properly specify many distinct cell fates along the long axis of the insect embryo. While the general molecular basis of this process has long been known in the fly Drosophila, detailed understanding of this process is still emerging in other insect species. What is now clear is that this process in extremely labile, and distinct AP patterning programs can exist even within a single species. This review presents recent progress on this topic in an attempt to synthesize the disparate data and provide an outlook on the future of the field.
前后轴模式形成是一个至关重要的过程，它需要产生大量的位置信息，以便沿着昆虫胚胎的长轴正确地指定许多不同的细胞命运。虽然在果蝇中，这一过程的一般分子基础早已为人所知，但在其他昆虫物种中，对这一过程的详细了解仍在不断涌现。现在清楚的是，这一过程极其不稳定，甚至在单一物种内也可能存在不同的前后轴模式形成程序。本综述介绍了该主题的最新进展，试图综合不同的数据，并展望该领域的未来。
