用超微血管成像和剪切波弹性成像评估幼年特发性关节炎患者的关节周围软组织
Evaluation of Periarticular Soft Tissues in Patients With Juvenile Idiopathic Arthritis by Superb Microvascular Imaging and Shear Wave Elastography.
作者信息
Ünal Ömer Faruk, BayramoĞlu Zuhal, Adaletlİ İbrahim
机构信息
Department of Radiology, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey.
出版信息
Arch Rheumatol. 2020 Feb 7;35(2):264-273. doi: 10.46497/ArchRheumatol.2020.7640. eCollection 2020 Jun.
OBJECTIVES
This study aims to compare the vascularity and elasticity of periarticular soft tissues by superb microvascular imaging (SMI) and power Doppler (PD) ultrasound along with shear wave elastography (SWE) between children with juvenile idiopathic arthritis (JIA) and healthy children.
PATIENTS AND METHODS
This prospective single center study, conducted between March 2018 and May 2018, included 22 children with JIA (14 males, 8 females; mean age 11.27±5 years; range, 5 to 17 years) and 24 healthy pediatric volunteers (12 males, 12 females; mean age 13±5.5 years; range, 7 to 17 years). Quadriceps tendon (QT), patellar tendon (PT), infraarticular and supraarticular soft tissue elasticities were calculated via SWE. Supraarticular and infraarticular soft tissue vascularity index (VI) were evaluated via SMI and PD.
RESULTS
No significant difference was found among the mean ages of the participants in study and control groups. Mean VI of both supraarticular (8.15%) and infraarticular soft tissues (7.9%) by SMI were significantly higher in study group compared to control group (2.88% vs. 2.57%, respectively). Mean VI of both supraarticular (9.1%) and infraarticular soft tissues (8.12%) by PD were significantly higher in study group compared to control group (3.4% vs. 3.1%, respectively). Highly significant good positive correlation was found between VI values obtained with PD and SMI (r=0.9, p=0.001). There was a significant moderate positive correlation between the mean elasticity of the QT with VI of the supraarticular soft tissues by SMI (r=0.4, p=0.003). There was a significant moderate positive correlation of VI of infraarticular soft tissues by SMI with mean elasiticity of PT (r=0.42, p=0.002).
CONCLUSION
Vascularity index by SMI and PD could differentiate patients with JIA from healthy subjects. The SWE examination of tendons and soft tissues did not show any significant difference among patients with JIA and healthy subjects.
目的
本研究旨在通过超微血管成像（SMI）、能量多普勒（PD）超声以及剪切波弹性成像（SWE）比较幼年特发性关节炎（JIA）患儿与健康儿童关节周围软组织的血管分布和弹性。
患者与方法
这项前瞻性单中心研究于2018年3月至2018年5月进行，纳入22例JIA患儿（男14例，女8例；平均年龄11.27±5岁；范围5至17岁）和24名健康儿科志愿者（男12例，女12例；平均年龄13±5.5岁；范围7至17岁）。通过SWE计算股四头肌肌腱（QT）、髌腱（PT）、关节内和关节上软组织的弹性。通过SMI和PD评估关节上和关节内软组织血管指数（VI）。
结果
研究组和对照组参与者的平均年龄之间未发现显著差异。与对照组相比，研究组通过SMI测得的关节上软组织（8.15%）和关节内软组织（7.9%）的平均VI均显著更高（分别为2.88%和2.57%）。与对照组相比，研究组通过PD测得的关节上软组织（9.1%）和关节内软组织（8.12%）的平均VI均显著更高（分别为3.4%和3.1%）。PD和SMI获得的VI值之间存在高度显著的良好正相关（r = 0.9，p = 0.001）。通过SMI测得的QT平均弹性与关节上软组织的VI之间存在显著的中度正相关（r = 0.4，p = 0.003）。通过SMI测得的关节内软组织的VI与PT的平均弹性之间存在显著的中度正相关（r = 0.42，p = 0.002）。
结论
SMI和PD的血管指数可区分JIA患者与健康受试者。JIA患者和健康受试者之间肌腱和软组织的SWE检查未显示任何显著差异。
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