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[骨内脑膜瘤一例报告]

[Report of a case of intraosseous meningioma].

作者信息

Kaneko F, Takase K, Nishiyama K, Kusaka K, Morizumi H, Matsumoto K

机构信息

Department of Neurosurgery, Tokushima Municipal Hospital, Japan.

出版信息

No Shinkei Geka. 1988 Feb;16(2):197-202.

PMID:3285234
Abstract

Cases of intraosseous meningioma appear to be very rare. In the present paper, we report such a case and discuss its etiological histogenesis on the basis of a review of 26 cases previously reported. A 71-year-old female was admitted to our department because of a painless mass in the right parietal region. Neurological findings were normal. Plain skull radiograph showed a 6 X 5-cm osteolytic lesion in the right fronto-parietal bone. CT scan demonstrated this lesion as a mass showing homogeneous enhancement with contrast medium. A right common carotid angiogram showed an avascular area in the parietal region and no tumor stain. The tumor, which was partly attached to the underlying dura, was totally removed surgically, and the postoperative course was uneventful. Histological examination of the specimen revealed fibroblastic meningioma, which was limited only to the outer membrane of the dura. The inner membrane was intact and free of tumor invasion. The histogenesis of intraosseous meningioma is still controversial but the following theories seem to be widely accepted: (1) The tumor arises from a part of the dura which has become trapped in a suture during embryological development. (2) The tumor arises from a part of the dura which has become trapped in a suture due to pressure on the head during delivery. (3) The tumor arises from a part of the dura which has become trapped in the bone due to trauma. (4) The dura which has become trapped in a suture during embryological development may undergo neoplastic change following traumatic stimulation.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

骨内脑膜瘤病例似乎非常罕见。在本文中,我们报告了这样一例病例,并在回顾先前报道的26例病例的基础上讨论其病因组织发生学。一名71岁女性因右顶叶无痛性肿块入住我科。神经系统检查结果正常。颅骨平片显示右额顶骨有一个6×5厘米的溶骨性病变。CT扫描显示该病变为一个肿块,注入造影剂后呈均匀强化。右侧颈总动脉血管造影显示顶叶区域无血管区且无肿瘤染色。肿瘤部分附着于下方硬脑膜,手术将其完全切除,术后病程顺利。对标本的组织学检查显示为纤维母细胞性脑膜瘤,仅局限于硬脑膜的外层。内层完整,无肿瘤侵犯。骨内脑膜瘤的组织发生学仍存在争议,但以下理论似乎被广泛接受:(1)肿瘤起源于胚胎发育过程中陷入缝线的硬脑膜部分。(2)肿瘤起源于分娩时头部受压导致陷入缝线的硬脑膜部分。(3)肿瘤起源于因创伤而陷入骨内的硬脑膜部分。(4)胚胎发育过程中陷入缝线的硬脑膜在受到创伤刺激后可能发生肿瘤性改变。(摘要截断于250字)

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