Discipline of Ophthalmology, Save Sight Institute.
Department of Ophthalmology, The Children's Hospital at Westmead.
J Glaucoma. 2020 Dec;29(12):1132-1137. doi: 10.1097/IJG.0000000000001645.
Glaucoma associated with Sturge-Weber syndrome (SWS) often requires surgical intervention. Our study shows that trabeculectomy is efficacious in treating this condition.
The purpose of this study was to describe the surgical outcomes of glaucoma associated with SWS in children presenting to the tertiary Paediatric Ophthalmology Department at The Children's Hospital at Westmead.
A retrospective study of patients with SWS referred to the Department of Ophthalmology at The Children's Hospital at Westmead between 2003 and 2016 with at least 2 years of follow-up were identified, and information was collected from the clinical notes of all subjects.
A total of 27 patients with SWS were evaluated for glaucoma in which 8 were excluded due to inadequate follow-up. In total, 19 patients with SWS were included in this study in which glaucoma was diagnosed in 15 patients and 19 eyes, of which 13 eyes required glaucoma surgery. A total of 21 surgical procedures were performed with a median follow-up of 85 months. A primary trabeculotomy was performed in 5 eyes of which 4 required re-do trabeculotomy, and 3 of these eyes underwent a Baerveldt tube (BVT) shunt as a third procedure. One eye with a primary trabeculotomy underwent a BVT as a secondary procedure. A BVT was inserted in a total of 6 eyes in which it was a primary procedure in 2 eyes. Of the 6 eyes undergoing a BVT insertion, 5 achieved success (2 complete and 3 qualified), and 1 failed. One case underwent intraluminal stent removal. Six eyes underwent a primary trabeculectomy and needed no further surgical intervention. In the trabeculectomy group, 4 eyes achieved complete success and 2 eyes achieved qualified success.
Glaucoma affects a significant proportion of patients with SWS and is associated with the presence of an ipsilateral port-wine stain in most cases. In our study, trabeculectomy was the most efficacious procedure for controlling intraocular pressure and reducing the burden of ongoing treatment in SWS-associated glaucoma.
与 Sturge-Weber 综合征（SWS）相关的青光眼通常需要手术干预。我们的研究表明，小梁切除术治疗这种疾病是有效的。
本研究旨在描述在西悉尼儿童医院眼科就诊的 SWS 患儿中与 SWS 相关的青光眼的手术结果。
对 2003 年至 2016 年期间在西悉尼儿童医院眼科就诊且至少有 2 年随访的 SWS 患者进行了回顾性研究，从所有患者的临床记录中收集了信息。
共评估了 27 例 SWS 合并青光眼患者，其中 8 例因随访不足而被排除。共有 19 例 SWS 患者纳入本研究，其中 15 例患者的 19 只眼被诊断为青光眼，其中 13 只眼需要青光眼手术。共进行了 21 次手术，中位随访时间为 85 个月。5 只眼行初次小梁切开术，其中 4 只眼需要再次行小梁切开术，其中 3 只眼行第三眼 Baerveldt 管（BVT）分流术。1 只眼行初次小梁切开术，二期行 BVT。共 6 只眼行 BVT 植入术，其中 2 只为初次手术。在这 6 只眼行 BVT 植入术的患者中，5 只眼（2 只完全成功，3 只合格）获得成功，1 只眼失败。1 例患者行内支架取出术。6 只眼行初次小梁切除术，无需进一步手术干预。在小梁切除术组中，4 只眼完全成功，2 只眼合格成功。
青光眼影响了很大一部分 SWS 患者，且大多数病例与同侧葡萄酒色斑的存在有关。在我们的研究中，小梁切除术是控制眼压和减少 SWS 相关青光眼治疗负担最有效的方法。
