Smith Geoffrey A, Levinson Anya L, Galvin Robert T, Lalor Leah E, McCalmont Timothy, Wang Linlin, Geis Michael C, Odegaard Karah, Hupp Meghan, Maguiness Sheilagh, Turcotte Lucie M, Cordoro Kelly M, Hermiston Michelle L
Division of Hematology/Oncology, University of California San Francisco Benioff Children's Hospital.
Departments of Pediatrics.
J Pediatr Hematol Oncol. 2021 Aug 1;43(6):e791-e794. doi: 10.1097/MPH.0000000000001921.
Subcutaneous panniculitis-like T-cell lymphoma is a cutaneous lymphoma characterized by CD8+ T-cell infiltrate in the subcutis that is rare in children. Acute lymphoblastic lymphoma is the most common pediatric malignancy and often presents with fevers and pancytopenia. Herein, we report 2 pediatric patients presenting with subcutaneous panniculitis-like T-cell lymphoma and B-cell acute lymphoblastic lymphoma, distinct hematologic malignancies arising from different lymphoid lineages, with no identifiable germline cancer predisposition.
皮下脂膜炎样T细胞淋巴瘤是一种皮肤淋巴瘤，其特征为皮下组织有CD8 + T细胞浸润，在儿童中较为罕见。急性淋巴细胞白血病是最常见的儿童恶性肿瘤，常表现为发热和全血细胞减少。在此，我们报告2例儿科患者，分别患有皮下脂膜炎样T细胞淋巴瘤和B细胞急性淋巴细胞白血病，这是源自不同淋巴谱系的不同血液系统恶性肿瘤，且无明确的种系癌症易感性。
