单瓣式心瓣膜在法洛四联症中并不能改善早期手术死亡率：一项荟萃分析。
Monocusp Valves Do Not Improve Early Operative Mortality in Tetralogy of Fallot: A Meta-Analysis.
机构信息
Department of Surgery, School of Medicine, 108330University of Nairobi, Kenyatta National Hospital, Nairobi, Kenya.
Department of Pediatrics, 7274Seattle Children's Hospital, Seattle, WA, USA.
出版信息
World J Pediatr Congenit Heart Surg. 2020 Sep;11(5):619-624. doi: 10.1177/2150135120934763.
Monocusp valves are thought to reduce early operative mortality and morbidity associated with pediatric tetralogy of Fallot repair. As there are no published randomized clinical trials comparing outcomes with and without a monocusp valve, we performed a meta-analysis of observational studies in accordance with established protocols. After systematically searching PubMed, the Cochrane Library, and Google Scholar, 12 studies were included. The operative mortality was compared in 695 patients, and we found no difference between patients with and patients without a monocusp valve. Monocusp valves may not improve operative mortality of tetralogy of Fallot repair in pediatric patients.
单瓣阀门被认为可以降低与小儿法洛四联症修复相关的早期手术死亡率和发病率。由于没有发表比较使用和不使用单瓣阀门的随机临床试验结果，我们根据既定方案对观察性研究进行了荟萃分析。经过系统地在 PubMed、Cochrane 图书馆和 Google Scholar 中搜索，纳入了 12 项研究。在 695 例患者中比较了手术死亡率，我们发现使用和不使用单瓣阀门的患者之间没有差异。对于小儿法洛四联症患者，单瓣阀门可能不会改善手术死亡率。
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