Stavros Niarchos Foundation Complex Joint Reconstruction Center, Hospital for Special Surgery,New York, USA.
Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Rome, Italy.
J Biol Regul Homeost Agents. 2020 May-Jun;34(3 Suppl. 2):57-62. ADVANCES IN MUSCULOSKELETAL DISEASES AND INFECTIONS - SOTIMI 2019.
Periprosthetic Joint Infection (PJI) of the Hip and of the Knee is a tremendous complication associated with high patient morbidity, cost, and increased health care resource utilization. Over the last few years, several perioperative strategies have been developed in the hopes of reducing the risk of early superficial and deep surgical site infection (SSI). One of the most performed intraoperative treatments to reduce the risk of SSI in total joint arthroplasty is the use of dilute povidone-iodine (DPI) irrigation prior to wound closure. For this reason, we believed a systematic review of the literature was needed to better understand the current literature on the efficacy of dilute betadine in reducing PJI. The search terms for this systematic review was performed for keywords "betadine", "povidone-iodine", "lavage", "irrigation" and "arthroplasty". A total of six studies were included, four of these reported the outcome of primary total joint arthroplasty, and two of these reported the outcome of revision total joint arthroplasty. Some studies reported that the use of DPI is effective to reduce the incidence of infective complications, meanwhile other studies did not find differences when DPI was used. More studies must be addressed to provide the efficacy of DPI irrigation.
髋关节和膝关节假体周围关节感染（PJI）是一种严重的并发症，与高患者发病率、高成本和增加医疗资源利用有关。在过去的几年中，已经开发了几种围手术期策略，希望降低早期浅表和深部手术部位感染（SSI）的风险。在全关节置换术中，为降低 SSI 风险而进行的最常见的术中治疗之一是在关闭伤口之前使用稀释聚维酮碘（DPI）冲洗。出于这个原因，我们认为需要对文献进行系统回顾，以更好地了解关于稀释洗必泰在降低 PJI 方面的疗效的现有文献。这个系统回顾的搜索词是针对关键字“洗必泰”、“聚维酮碘”、“灌洗”、“冲洗”和“关节置换术”进行的。共纳入了六项研究，其中四项报告了初次全关节置换术的结果，两项报告了翻修全关节置换术的结果。一些研究报告称，使用 DPI 可有效降低感染性并发症的发生率，而其他研究则发现使用 DPI 没有差异。必须进行更多的研究以提供 DPI 冲洗的疗效。
