脊柱裂胎儿的小脑发育不全。

Subnormal cerebellum in fetuses with spina bifida.

作者信息

Pilu G, Romero R, Reece E A, Goldstein I, Hobbins J C, Bovicelli L

机构信息

2nd Department of Obstetrics and Gynecology, University of Bologna School of Medicine, Italy.

出版信息

Am J Obstet Gynecol. 1988 May;158(5):1052-6. doi: 10.1016/0002-9378(88)90218-9.

DOI:10.1016/0002-9378(88)90218-9

PMID:3285683

Abstract

The results of a prospective ultrasound study of the posterior fossa structures in 19 fetuses with spina bifida are reported. The transverse cerebellar diameter is below the normal limits and the cisterna magna is obliterated in all cases. Decreased cerebellar size and failure to visualize the cerebellum appear to be specific findings for spina bifida since they are not present in a group of 17 fetuses with isolated hydrocephalus. The results of this study indicate that ultrasound investigation of the posterior fossa may prove useful in the prenatal diagnosis of spina bifida.

摘要

报告了一项对19例脊柱裂胎儿后颅窝结构进行的前瞻性超声研究结果。所有病例中，小脑横径均低于正常范围，枕大池消失。小脑体积减小以及小脑无法显影似乎是脊柱裂的特异性表现，因为在一组17例单纯脑积水胎儿中未出现这些情况。本研究结果表明，后颅窝超声检查可能在脊柱裂的产前诊断中发挥作用。