Sramek J, Herrera J, Costa J, Heh C, Tran-Johnson T, Simpson G
Clinical Research Unit, Metropolitan State Hospital, Norwalk, CA 90650.
Am J Psychiatry. 1988 Jun;145(6):748-50. doi: 10.1176/ajp.145.6.748.
Carbamazepine was given to 12 chronic, treatment-refractory schizophrenic patients for 5 weeks. No overall change was found, but four patients significantly improved while eight worsened. Given the paucity of successful treatments for refractory schizophrenia, further study of carbamazepine appears warranted.
对12名慢性难治性精神分裂症患者给予卡马西平治疗5周。未发现总体变化,但4名患者病情显著改善,8名患者病情恶化。鉴于难治性精神分裂症成功治疗方法匮乏,卡马西平的进一步研究似乎很有必要。