Institutes of Physics Science and Information Technology, Key Laboratory of Structure and Functional Regulation of Hybrid Materials, Ministry of Education, Anhui University, Hefei 230601, P. R. China.
Department of Chemistry, Key Laboratory of Functional Inorganic Material Chemistry of Anhui Province, Anhui University, Hefei 230601, P. R. China.
Inorg Chem. 2020 Sep 21;59(18):13671-13678. doi: 10.1021/acs.inorgchem.0c02030. Epub 2020 Aug 28.
The construction of novel classes of photosensitizers for efficient reactive oxygen species (ROS) generation is of great interest, yet it is a challenge. In this work, a bis(terpyridine)zinc(II) complex (namely, ) with two-photon absorption activity as an efficient ROS photogenerator was synthesized. Benefiting from the coordinated Zn, the decreased singlet-triplet energy gap favors the intersystem crossing process facilitating the singlet oxygen (O) generation via energy transfer. In addition, it makes the superoxide radical (O) generation easier. This is an extremely rare study on two-photon excited ROS generation by activating type I and type II processes based on a cheaper and bioaccessible Zn complex.
新型光活性氧（ROS）生成剂的构建具有重要意义，但极具挑战性。本工作合成了一种具有双光子吸收活性的双（三联吡啶）锌（II）配合物（即 ）作为高效的 ROS 光发生器。受益于配位的 Zn，降低的单重态-三重态能量间隙有利于通过能量转移促进单线态氧（O）的生成。此外，它还使得超氧自由基（O）的生成更容易。这是基于更便宜且生物可及的 Zn 配合物通过激活 I 型和 II 型过程来研究双光子激发 ROS 生成的极为罕见的研究。
