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小儿乳腺脓肿的特征及最佳治疗方法:回顾性分析。

Characterization of Pediatric Breast Abscesses and Optimal Treatment: A Retrospective Analysis.

机构信息

Department of Surgery, Children's Mercy Kansas City, Kansas City, Missouri.

School of Medicine, University of Missouri Kansas City, Kansas City, Missouri.

出版信息

J Surg Res. 2021 Jan;257:195-202. doi: 10.1016/j.jss.2020.07.014. Epub 2020 Aug 25.

Abstract

BACKGROUND

Literature on pediatric breast abscesses is sparse; therefore, treatment is based on adult literature which has shifted from incision and drainage (I&D) to needle aspiration. However, children may require different treatment due to different risk factors and the presence of a developing breast bud. We sought to characterize pediatric breast abscesses and compare outcomes.

MATERIALS AND METHODS

A retrospective review of patients presenting with a primary breast abscess from January 2008 to December 2018 was conducted. Primary outcome was persistent disease. Antibiotic utilization, treatment required, and risk factors for abscess and recurrence were also assessed. A follow-up survey regarding scarring, deformity, and further procedures was administered. Fisher's exact and Kruskal-Wallis tests for group comparisons and multivariable regression to determine associations with recurrence were performed.

RESULTS

Ninety-six patients were included. The median age was 12.8 y [IQR 4.9, 14.3], 81% were women, and 51% were African-American. Most commonly, patients were treated with antibiotics alone (47%), followed by I&D (27%), and aspiration (26%). Twelve patients (13%) had persistent disease. There was no difference in demographic or clinical characteristics between those with persistent disease and those who responded to initial treatment. The success rates of primary treatment were 80% with antibiotics alone, 90% with aspiration, and 96% with I&D (P = 0.35). The median time to follow-up survey was 6.5 y [IQR 4.4, 8.5]. Four patients who underwent I&D initially reported significant scarring.

CONCLUSIONS

Treatment modality was not associated with persistent disease. A trial of antibiotics alone may be considered to minimize the risk of breast bud damage and adverse cosmetic outcomes with invasive intervention.

摘要

背景

小儿乳腺脓肿的文献资料较少;因此,治疗方法基于成人文献,成人文献已经从切开引流(I&D)转为针吸。然而,由于不同的风险因素和发育中的乳腺芽的存在,儿童可能需要不同的治疗方法。我们旨在描述小儿乳腺脓肿的特征,并比较其结果。

材料和方法

对 2008 年 1 月至 2018 年 12 月期间因原发性乳腺脓肿就诊的患者进行了回顾性研究。主要结局是持续性疾病。还评估了抗生素的使用、所需的治疗以及脓肿和复发的风险因素。对疤痕、畸形和进一步手术的情况进行了随访调查。使用 Fisher 确切检验和 Kruskal-Wallis 检验进行组间比较,使用多变量回归分析确定与复发相关的因素。

结果

共纳入 96 例患者。中位年龄为 12.8 岁[四分位距(IQR)4.9,14.3],81%为女性,51%为非裔美国人。最常见的治疗方法是单独使用抗生素(47%),其次是切开引流(27%)和抽吸(26%)。12 例(13%)患者存在持续性疾病。持续性疾病患者与初始治疗有效患者的人口统计学和临床特征无差异。单独使用抗生素、抽吸和切开引流的初始治疗成功率分别为 80%、90%和 96%(P=0.35)。随访调查的中位时间为 6.5 年[IQR 4.4,8.5]。4 例最初接受切开引流的患者报告有明显的疤痕。

结论

治疗方式与持续性疾病无关。单独使用抗生素可能是一种可行的方法,可以尽量减少乳腺芽损伤和侵入性干预的不良美容结局的风险。

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