Chen Chang-Chun, Lin Cheng-Yu, Chen Yen-Chin, Ko Wen-Chien, Li Chung-Yi, Ko Nai-Ying
International Doctoral Program in Nursing, Department of Nursing, National Cheng Kung University, No.1, University Road, Tainan City 70101, Taiwan.
Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan City, 70403, Taiwan; Sleep Medicine Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan City, 70403, Taiwan.
Sleep Med. 2020 Nov;75:218-224. doi: 10.1016/j.sleep.2020.07.005. Epub 2020 Jul 20.
Sleep-related breathing disorders (SRBD) not only adversely impact cardiovascular and pulmonary functions but also reduce the quality of life. This study attempted to investigate the severity and related factors of SRBD among human immunodeficiency virus (HIV)-infected people with sleep complaints.
A cross-sectional study was conducted among HIV-infected people with Pittsburgh Sleep Quality Index (PSQI) values above 5 points. SRBDs were defined as Apnea-Hypopnea Index (AHI) over 5 events/hour by full channel home-based polysomnography (PSG). An AHI greater than 30 was categorized as moderate to severe apnea. All of the participants were asked to rate the severity of their snoring, complete a snore outcomes survey (SOS) and complete the PSQI. Multiple logistic regression analysis was conducted to examine the associated factors of severity of SRBD among HIV-infected people.
Of 54 male HIV-positive patients with sleep complaints, 34 subjects (62.96%) were diagnosed with SRBDs, and 29.63% were categorized as having moderate to severe SRBD. SOS score was significantly associated with HIV patients with moderate to severe SRBD (adjusted odds ratio = 0.93, 95% CI: 0.87-1.00, p = 0.045).
SRBDs is highly prevalent in male HIV-infected people with sleep complaints. Intensive snoring was one of the indicators associated with the occurrence of moderate to severe SRBDs among HIV-infected people. Healthcare professionals should include snoring screening in the regular course of clinical HIV care.
睡眠相关呼吸障碍（SRBD）不仅对心血管和肺功能产生不利影响，还会降低生活质量。本研究旨在调查有睡眠主诉的人类免疫缺陷病毒（HIV）感染者中SRBD的严重程度及相关因素。
对匹兹堡睡眠质量指数（PSQI）值高于5分的HIV感染者进行了一项横断面研究。通过全通道家庭多导睡眠图（PSG）将SRBD定义为呼吸暂停低通气指数（AHI）超过5次/小时。AHI大于30被归类为中度至重度呼吸暂停。所有参与者都被要求对自己打鼾的严重程度进行评分，完成打鼾结果调查（SOS）并完成PSQI。进行多因素逻辑回归分析以检查HIV感染者中SRBD严重程度的相关因素。
在54名有睡眠主诉的男性HIV阳性患者中，34名受试者（62.96%）被诊断患有SRBD，29.63%被归类为患有中度至重度SRBD。SOS评分与中度至重度SRBD的HIV患者显著相关（调整后的优势比=0.93，95%置信区间：0.87-1.00，p=0.045）。
SRBD在有睡眠主诉的男性HIV感染者中非常普遍。严重打鼾是HIV感染者中与中度至重度SRBD发生相关的指标之一。医疗保健专业人员应在常规HIV临床护理过程中纳入打鼾筛查。
