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一项关于确诊糖尿病出院患者死亡风险因素的系统评价。

A systematic review considering risk factors for mortality of patients discharged from hospital with a diagnosis of diabetes.

作者信息

Mukherjee Teesta, Robbins Tim, Lim Choi Keung Sarah N, Sankar Sailesh, Randeva Harpal, Arvanitis Theodoros N

机构信息

Institute of Digital Healthcare, WMG, University of Warwick, Coventry CV4 7AL, United Kingdom.

Institute of Digital Healthcare, WMG, University of Warwick, Coventry CV4 7AL, United Kingdom; University Hospitals Coventry & Warwickshire NHS Trust, Clifford Bridge Road, Coventry CV2 2DX, United Kingdom.

出版信息

J Diabetes Complications. 2020 Nov;34(11):107705. doi: 10.1016/j.jdiacomp.2020.107705. Epub 2020 Aug 4.

Abstract

AIM

To identify known risk factors for mortality for adult patients, discharged from hospital with diabetes.

METHOD

The systematic review was based on the PRISMA protocol. Studies were identified through EMBASE & MEDLINE databases. The inclusion criteria were papers that were published over the last 6 years, in English language, and focused on risk factors of mortality in adult patients with diabetes, after they were discharged from hospitals. This was followed by data extraction "with quality assessment and semi-quantitative synthesis according to PRISMA guidelines".

RESULTS

There were 35 studies identified, considering risk factors relating to mortality for patients, discharged from hospital with diabetes. These studies are distributed internationally. 48 distinct statistically significant risk factors for mortality can be identified. Risk factors can be grouped into the following categories; demographic, socioeconomic, lifestyle, patient medical, inpatient stay, medication related, laboratory results, and gylcaemic status. These risk factors can be further divided into risk factors identified in generalized populations of patients with diabetes, compared to specific sub-populations of people with diabetes.

CONCLUSION

A relatively small number of studies have considered risk factors relating to mortality for patients, discharged from hospital with a diagnosis of diabetes. Mortality is an important outcome, when considering discharge from hospital with diabetes. However, there has only been limited consideration within the research literature.

摘要

目的

确定成年糖尿病患者出院后的已知死亡风险因素。

方法

系统评价基于PRISMA方案。通过EMBASE和MEDLINE数据库检索研究。纳入标准为过去6年发表的英文论文,且聚焦于成年糖尿病患者出院后的死亡风险因素。随后根据PRISMA指南进行数据提取、质量评估和半定量综合分析。

结果

共确定了35项研究,涉及糖尿病出院患者的死亡风险因素。这些研究分布在国际上。可识别出48个不同的具有统计学意义的死亡风险因素。风险因素可分为以下几类:人口统计学、社会经济、生活方式、患者医疗、住院时间、药物相关、实验室检查结果和血糖状态。与糖尿病特定亚人群相比,这些风险因素还可进一步分为在糖尿病患者一般人群中确定的风险因素。

结论

相对较少的研究考虑了糖尿病诊断出院患者的死亡风险因素。在考虑糖尿病患者出院时,死亡是一个重要结局。然而,研究文献中对此的考虑有限。

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