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641 例亚急性缺血性脑卒中患者的高频高强度康复治疗。

High Frequency and Intensity Rehabilitation in 641 Subacute Ischemic Stroke Patients.

机构信息

Somogy County Móricz Kaposi Teaching Hospital, Kaposvár, Hungary; University of Pécs, Faculty of Health Sciences, Doctoral School of Health Sciences, Pécs, Hungary.

Somogy County Móricz Kaposi Teaching Hospital, Kaposvár, Hungary; University of Pécs, Faculty of Health Sciences, Doctoral School of Health Sciences, Pécs, Hungary.

出版信息

Arch Phys Med Rehabil. 2021 Jan;102(1):9-18. doi: 10.1016/j.apmr.2020.07.012. Epub 2020 Aug 27.

DOI:10.1016/j.apmr.2020.07.012
PMID:32861668
Abstract

OBJECTIVES

To determine the effects of exergaming on quality of life (QoL), motor, and clinical symptoms in subacute stroke patients.

DESIGN

A pseudorandomized controlled trial, using a before-after test design.

SETTING

University hospital.

PARTICIPANTS

Subacute, ischemic stroke outpatients (N=3857), 680 of whom were randomized and 641 completed the study.

INTERVENTIONS

We determined the effects of 5 times a week twice daily (EX2; 50 sessions; n=286) and once daily (EX1; 25 sessions; n=272) exergaming and low-intensity standard care (control [CON]; 25 sessions; n=83) on clinical, mobility, blood pressure (BP), and QoL outcomes.

MAIN OUTCOME MEASURES

The primary outcome was Modified Rankin Scale. Secondary outcomes were activities of daily living, 5 aspects of health-related QoL, Beck Depression Inventory, 6-minute walk test (6MWT), Berg Balance Scale (BBS), and static balance (center of pressure).

RESULTS

During exercise, the peak heart rate was 134, 134, and 126 beats per minute in the EX2, EX1, and CON groups, respectively. mRS improved similarly in the EX2 (-1.8; effect size, d=-4.0) and EX1 (-1.4; d=-2.6) groups, but more than in the CON group (-0.7; d=-0.6). QoL, Barthel Index, BBS, 6MWT, and standing posturography improved more in the EX2 group and the same in the EX1 and CON groups. Systolic and diastolic resting BP decreased more in the EX2 and EX1 groups than in the CON group. The intervention effects did not differ between men (n=349) and women (n=292).

CONCLUSIONS

Twice daily compared with once daily high-intensity exergaming or once daily lower intensity standard care produced superior effects on clinical and motor symptoms, BP, and QoL in male and female subacute ischemic stroke participants.

摘要

目的

探讨运动游戏对亚急性脑卒中患者生活质量(QoL)、运动功能和临床症状的影响。

设计

采用伪随机对照试验,采用前后测试设计。

地点

大学医院。

参与者

亚急性缺血性脑卒中门诊患者(N=3857),其中 680 例被随机分组,641 例完成研究。

干预措施

每周 5 次,每天 2 次(EX2;50 次;n=286)和每天 1 次(EX1;25 次;n=272)的运动游戏和低强度标准护理(对照组[CON];25 次;n=83)对临床、移动性、血压(BP)和生活质量结果的影响。

主要观察指标

主要结局为改良 Rankin 量表。次要结局为日常生活活动、健康相关生活质量的 5 个方面、贝克抑郁量表、6 分钟步行试验(6MWT)、伯格平衡量表(BBS)和静态平衡(压力中心)。

结果

运动时,EX2、EX1 和 CON 组的峰值心率分别为 134、134 和 126 次/分钟。EX2(-1.8;效应大小,d=-4.0)和 EX1(-1.4;d=-2.6)组的 mRS 改善相似,但优于 CON 组(-0.7;d=-0.6)。EX2 组的 QoL、巴氏指数、BBS、6MWT 和站立姿势描记术改善更明显,EX1 组和 CON 组相同。与 CON 组相比,EX2 和 EX1 组的收缩压和舒张压休息时降低更多。男性(n=349)和女性(n=292)的干预效果无差异。

结论

与每日一次的高强度运动游戏或每日一次的低强度标准护理相比,每日两次的高强度运动游戏对男性和女性亚急性缺血性脑卒中患者的临床和运动症状、BP 和 QoL 有更好的效果。

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