Department of Medicine and Therapeutics, College of Health Sciences, University of Ghana Medical School, Legon, Accra, Ghana.
Division of Endocrinology, Diabetes and Metabolism, Penn State Medical Center, Penn State University, Hershey, Pennsylvania, U.S.A.
Ghana Med J. 2020 Mar;54(1):58-67. doi: 10.4314/gmj.v54i1.9.
Data abounds on osteoporosis in developed countries unlike developing countries, particularly those in sub-Saharan Africa. This review was done to confirm the paucity of data the authors suspected and to encourage studies in this field. AJOL (African Journals Online), MEDLINE and EMBASE databases were searched for studies published from January 1980 to August 2018. The eligibility criteria for inclusion were observational studies evaluating osteoporosis prevalence or incidence rates of fragility fractures. Out of 1,170 articles identified, six met the eligibility criteria. Prevalence of osteoporosis ranged from 18.2% to 65.8% across a heterogenous at-risk population. Bone mineral density assessment was limited by the measurement method, with most studies using quantitative ultrasound instead of standard bone densitometry. From the available studies, the prevalence of osteoporosis and fragility fracture incidence may not be low in Sub-Saharan Africa; what is, however, evident is the paucity of good quality data from this region. Considering an expected aging population in sub-Saharan Africa, future research should be encouraged and aimed at clarifying the burden of this non-communicable disease. This will guide healthcare policy in this medically underserved part of Africa.
None declared.
与发达国家相比,发展中国家,尤其是撒哈拉以南非洲国家,有关骨质疏松的数据很少。本研究旨在证实作者所怀疑的资料匮乏情况,并鼓励该领域的研究。通过 AJOL(非洲期刊在线)、MEDLINE 和 EMBASE 数据库,检索了 1980 年 1 月至 2018 年 8 月发表的研究。纳入标准为评估骨质疏松症患病率或脆性骨折发病率的观察性研究。在确定的 1170 篇文章中,有 6 篇符合入选标准。在不同的高危人群中,骨质疏松症的患病率从 18.2%到 65.8%不等。骨矿物质密度评估受到测量方法的限制,大多数研究使用定量超声而不是标准骨密度测定法。从现有的研究来看,骨质疏松症和脆性骨折的发病率在撒哈拉以南非洲可能不低;然而,明显的是,该地区缺乏高质量的数据。考虑到撒哈拉以南非洲地区预期的人口老龄化,应该鼓励开展未来的研究,以明确这一非传染性疾病的负担。这将为非洲这个医疗服务不足地区的医疗保健政策提供指导。
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