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一名溃疡性结肠炎患者并发伊文氏综合征的罕见病例。

A Rare Case of Evans Syndrome in a Patient With Ulcerative Colitis.

作者信息

Chan Kok Hoe, Lim Su Lin, Are Gowthami, DaCosta Theodore, Shaaban Hamid S

机构信息

Department of Medical Education, Saint Michael's Medical Center, New York Medical College, Newark, NJ 07101, USA.

Department of Internal Medicine, Saint Michael's Medical Center, New York Medical College, Newark, NJ 07101, USA.

出版信息

Gastroenterology Res. 2020 Aug;13(4):158-160. doi: 10.14740/gr1316. Epub 2020 Aug 14.

Abstract

Evans syndrome (ES) is an autoimmune condition that presents with two or more cytopenias, which includes simultaneous or sequential development of warm autoimmune hemolytic anemia (AIHA) and immune thrombocytopenic purpura (ITP). The association of ES with ulcerative colitis (UC) was only reported once in the literature. Herein, we present a case of a 66-year-old male patient with a history of UC, who was diagnosed with ES secondary to UC, for which he was treated with steroids. Recognizing this rare association is important as prompt treatment with intravenous immunoglobulin and steroids will improve the prognosis and reduce the risk of complications.

摘要

伊文斯综合征(ES)是一种自身免疫性疾病,表现为两种或更多种血细胞减少,包括温抗体型自身免疫性溶血性贫血(AIHA)和免疫性血小板减少性紫癜(ITP)同时或相继发生。ES与溃疡性结肠炎(UC)的关联在文献中仅被报道过一次。在此,我们报告一例66岁男性患者,有UC病史,被诊断为继发于UC的ES,为此他接受了类固醇治疗。认识到这种罕见的关联很重要,因为及时使用静脉注射免疫球蛋白和类固醇进行治疗将改善预后并降低并发症风险。

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本文引用的文献

1
A Case of Evan's Syndrome Induced by Vedolizumab.维多珠单抗诱发伊文氏综合征一例。
ACG Case Rep J. 2019 Feb 13;6(1):e00002. doi: 10.14309/crj.0000000000000002. eCollection 2019 Jan.
8
Management of Evans syndrome.伊文氏综合征的管理
Br J Haematol. 2006 Jan;132(2):125-37. doi: 10.1111/j.1365-2141.2005.05809.x.

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