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Comparison of effects of proglumide and CR 1409, a new glutaramic acid derivative, on CCK-8-induced pancreatic polypeptide and insulin secretion in the dog.

作者信息

Inui A, Oya M, Inoue T, Sakatani N, Morioka H, Baba S

机构信息

Second Department of Internal Medicine, School of Medicine, Kobe University, Hyogo, Japan.

出版信息

Horm Metab Res. 1988 Jan;20(1):61-2. doi: 10.1055/s-2007-1010749.

DOI:10.1055/s-2007-1010749
PMID:3286447
Abstract
摘要

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1
Comparison of effects of proglumide and CR 1409, a new glutaramic acid derivative, on CCK-8-induced pancreatic polypeptide and insulin secretion in the dog.丙谷胺与新型谷氨酸衍生物CR 1409对犬胆囊收缩素-8诱导的胰多肽和胰岛素分泌影响的比较。
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Proglumide analogues CR 1409 and CR 1392 inhibit cholecystokinin-stimulated insulin release more potently than exocrine secretion from the isolated perfused rat pancreas.丙谷胺类似物CR 1409和CR 1392对胆囊收缩素刺激的胰岛素释放的抑制作用，比其对离体灌注大鼠胰腺外分泌的抑制作用更强。
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Effects of three different cholecystokinin receptor antagonists on basal and stimulated insulin and glucagon secretion in mice.三种不同的胆囊收缩素受体拮抗剂对小鼠基础及刺激状态下胰岛素和胰高血糖素分泌的影响
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[The effect of cholecystokinin antagonists on satiety induced by cholecystokinin octapeptide in dogs].[胆囊收缩素拮抗剂对犬胆囊收缩素八肽诱导饱腹感的影响]
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