Department of Environmental Toxicology and Research, Korea Institute of Toxicology, Jinju, 52834, Republic of Korea.
Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea.
Bull Environ Contam Toxicol. 2020 Oct;105(4):656-664. doi: 10.1007/s00128-020-02976-w. Epub 2020 Aug 31.
Methiozolin is a novel herbicide for controlling annual bluegrass. After applying C labelled methiozolin in two sediment (clay loam and sand)-water systems under aerobic conditions, its distribution, half-life, and metabolites within 300 days were investigated. The mass balance ranged within 92.0%-104.4% of applied radioactivity (AR). Radioactivity in the water declined sharply from 94.4% to 0.5% AR, while in the sediment it increased to 83.9% AR at 14 days before declining to 9.1% AR. The volatiles were minimal (< 0.5% AR), and the evolved labelled CO accounted for up to ~ 33.4% AR. From Radio-HPLC analysis, labelled methiozolin in water decreased from 108.9% to 0% AR, while a maximum of 15.1% AR remained in the sediment at the end. Eight metabolites were detected, all at minor levels and accounting for < 5.5% AR. The half-life of labelled methiozolin in the total sediment-water systems were 50.7 and 38.7 days for clay loam and sand, respectively.
甲硫基唑啉是一种新型除草剂，可用于防治一年生早熟禾。在有氧条件下，将 C 标记的甲硫基唑啉应用于两种沉积物（壤土和沙）-水系统中，研究了其在 300 天内的分布、半衰期和代谢物。质量平衡在施用量放射性（AR）的 92.0%-104.4% 范围内。水中的放射性物质迅速从 94.4%下降到 0.5%AR，而在沉积物中，它在 14 天内增加到 83.9%AR，然后下降到 9.1%AR。挥发物最少（<0.5%AR），释放的标记 CO 占最多可达~33.4%AR。从放射性 HPLC 分析中可以看出，水中的标记甲硫基唑啉从 108.9%下降到 0%AR，而在沉积物中，到最后仍有最多 15.1%AR 残留。检测到 8 种代谢物，均处于次要水平，占<5.5%AR。标记甲硫基唑啉在总沉积物-水系统中的半衰期分别为壤土和沙中的 50.7 和 38.7 天。
