Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Thorax. 2021 Mar;76(3):295-297. doi: 10.1136/thoraxjnl-2020-215085. Epub 2020 Aug 31.
Multiple CT indices are associated with disease progression and mortality in patients with COPD, but which indices have the strongest association remain unestablished. This longitudinal 10-year observational study (n=247) showed that the emphysema severity on CT is more closely associated with the progression of airflow limitation and that a reduction in the cross-sectional area of erector spinae muscles (ESM) on CT is more closely associated with mortality than the other CT indices, independent of patient demographics and pulmonary function. ESM is a useful CT index that is more closely associated with long-term mortality than emphysema and airway disease in patients with COPD.
多项 CT 指数与 COPD 患者的疾病进展和死亡率相关，但哪些指数具有最强的关联尚未确定。这项为期 10 年的纵向观察研究（n=247）表明，CT 上的肺气肿严重程度与气流受限的进展更为密切相关，而 CT 上竖脊肌（ESM）的横截面积减少与死亡率的关联更为密切，这与患者的人口统计学和肺功能无关。ESM 是一种有用的 CT 指数，与 COPD 患者的长期死亡率比肺气肿和气道疾病更为密切相关。
