Silesian University of Technology, Faculty of Chemistry, Department of Inorganic Chemistry, Analytical Chemistry and Electrochemistry, B. Krzywoustego 6 St, 44-100 Gliwice, Poland.
Institute for Chemical Processing of Coal, Zamkowa 1 St, 41-803 Zabrze, Poland.
J Chromatogr Sci. 2020 Sep 29;58(9):831-843. doi: 10.1093/chromsci/bmaa053.
The program of potato protection recommended by the producers of agrochemicals requires application: thiamethoxam, lambda-cyhalothrin, deltamethrin, rimsulfuron and metalaxyl. Therefore, there is a risk that these pesticides are present in tubers, thus posing a toxicological risk to the consumer. In this respect, it is necessary to monitor the presence of these compounds in edible plants. Therefore, the aim of this paper was to develop a novel, simple and robust analytical procedure for simultaneous determination of above-mentioned pesticides in potato tubers. To develop an analytical procedure that fulfills SANTE demands, quick, easy, cheap, effective, rugged and safe method and matrix solid phase dispersion technique were investigated. The final determination was conducted by liquid chromatography with tandem mass spectrometry. The obtained experimental data were analyzed by analysis of variance. For the extraction of analytes, matrix solid phase dispersion with octadecyl sorbent and methanol as eluent was chosen, since it provides the validation parameters according to SANTE requirements (recovery: 77-111%, relative standard deviation: 1-10%, limit of quantification: 0.9-5.0 μg/kg). This innovative analytical procedure is a practical analytical tool, which was successfully proven by applying it for target pesticides determination in potato tuber samples of different varieties randomly chosen at local markets.
农药生产商推荐的马铃薯保护计划要求使用噻虫嗪、高效氯氟氰菊酯、溴氰菊酯、苯磺隆和甲霜灵。因此，这些农药有可能存在于块茎中，从而对消费者构成毒理学风险。在这方面，有必要监测这些化合物在食用植物中的存在情况。因此，本文的目的是开发一种新颖、简单和强大的分析程序，用于同时测定马铃薯块茎中的上述农药。为了开发符合 SANTE 要求的分析程序，研究了快速、简单、廉价、有效、耐用和安全的方法和基质固相分散技术。最终的测定是通过液相色谱-串联质谱法进行的。通过方差分析对获得的实验数据进行了分析。对于分析物的提取，选择了基质固相分散法，用十八烷基填料和甲醇作为洗脱剂，因为它提供了符合 SANTE 要求的验证参数（回收率：77-111%，相对标准偏差：1-10%，定量限：0.9-5.0μg/kg）。这种创新的分析程序是一种实用的分析工具，已成功应用于当地市场随机选择的不同品种马铃薯块茎样品中目标农药的测定。
