Division of Histology and Embryology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland.
Department of Biomedical Engineering, Faculty of Mechanical Engineering, University of Zielona Góra, Zielona Góra, Poland.
Anat Histol Embryol. 2021 Jan;50(1):136-143. doi: 10.1111/ahe.12611. Epub 2020 Sep 1.
This stereudy aimed at performing a histological and morphometric evaluation of the urethra and penis of male rabbits. Seven male New Zealand White rabbits weighing 2.1-3 kg were used in the study. The whole urethra, from the urinary bladder to the external urethral orifice, was dissected from the rabbits, and the tissue was sliced into sections at an interval of 2 mm. The sections were stained with haematoxylin-eosin, Masson-Goldner trichrome stain, Van Gieson's stain and Movat-Russell modified pentachrome stain. A detailed evaluation of the morphology and morphometry was performed. The parameters assessed were the type and height of epithelium, thickness and composition of connective tissue, and thickness and structure of muscularis. The histological structure of the rabbit urethra was found to be similar to humans. However, although the rabbits were found to have the same type of penis as the humans, the internal structure of the corpora cavernosa, the relative thickness of the tunica albuginea and the rudimentary glands of the penis were found to differ in these animals. The results of the present study may be useful in the designing of implants, drug testing or surgical procedures on the physiological and pathological urethra.
本研究旨在对雄性新西兰白兔的尿道和阴茎进行组织学和形态计量学评估。研究使用了 7 只体重为 2.1-3 公斤的雄性新西兰白兔。从兔子身上解剖出整个尿道，从膀胱到尿道外口，并将组织切成 2 毫米间隔的切片。用苏木精-伊红、马松-戈尔登三色染色、范吉森染色和莫瓦特-拉塞尔改良五倍体染色对切片进行染色。对形态和形态计量学进行了详细评估。评估的参数包括上皮的类型和高度、结缔组织的厚度和组成以及平滑肌的厚度和结构。发现兔尿道的组织学结构与人相似。然而，尽管兔子的阴茎与人类相同，但发现其海绵体的内部结构、白膜的相对厚度和阴茎的原始腺体在这些动物中存在差异。本研究的结果可能有助于设计对生理和病理尿道的植入物、药物测试或手术程序。
