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[库欣综合征——支气管类癌的主要症状]

[Cushing syndrome--a leading symptom in bronchial carcinoid].

作者信息

Bier B, Seitz G, Weinheimer B

机构信息

Pathologisches Institut, Universität des Saarlandes, Homburg.

出版信息

Klin Wochenschr. 1988 Apr 1;66(7):314-22. doi: 10.1007/BF01727520.

DOI:10.1007/BF01727520
PMID:3286991
Abstract

Bilateral adrenalectomy was performed in a 27-year-old male because of Cushing's syndrome. After 7 years a peripheral bronchial carcinoid was diagnosed; ACTH values went back to normal only after removal of the carcinoid. In the literature, there are 31 case reports on bronchial carcinoids associated with Cushing's syndrome. The Cushing's syndrome precedes the diagnosis of a tumor for months to years in at least half of the cases. Most of these patients first underwent adrenalectomy and/or hypophysectomy for their primarily endocrine symptoms and signs.

摘要

一名27岁男性因库欣综合征接受了双侧肾上腺切除术。7年后,诊断出周围型支气管类癌;仅在切除类癌后,促肾上腺皮质激素(ACTH)值才恢复正常。文献中有31例关于支气管类癌与库欣综合征相关的病例报告。在至少一半的病例中,库欣综合征在肿瘤诊断前数月至数年出现。这些患者中的大多数最初因主要的内分泌症状和体征接受了肾上腺切除术和/或垂体切除术。

相似文献

1
[Cushing syndrome--a leading symptom in bronchial carcinoid].[库欣综合征——支气管类癌的主要症状]
Klin Wochenschr. 1988 Apr 1;66(7):314-22. doi: 10.1007/BF01727520.
2
[Cushing syndrome with occult ectopic ACTH production].[隐匿性异位促肾上腺皮质激素分泌所致库欣综合征]
Praxis (Bern 1994). 1999 Apr 8;88(15):679-85.
3
Ectopic ACTH syndrome caused by pulmonary carcinoid tumourlets.由肺类癌小结引起的异位促肾上腺皮质激素综合征。
Clin Endocrinol (Oxf). 2001 Jun;54(6):839-42. doi: 10.1046/j.1365-2265.2001.01114.x.
4
[Cushing's syndrome in bronchial carcinoid: suppressible ectopic ACTH selection].[支气管类癌中的库欣综合征:可抑制性异位促肾上腺皮质激素分泌型]
Schweiz Med Wochenschr. 1982 Oct 23;112(43):1507-14.
5
Cushing's syndrome caused by ectopic corticotropin secretion by multiple peripheral pulmonary carcinoids and tumorlets of carcinoid type.由多个外周肺类癌及类癌型微瘤异位分泌促肾上腺皮质激素引起的库欣综合征。
J Endocrinol Invest. 2000 Sep;23(8):536-41. doi: 10.1007/BF03343771.
6
[Cushing's syndrome with ectopic ACTH secretion].[异位促肾上腺皮质激素分泌所致库欣综合征]
Rev Med Chir Soc Med Nat Iasi. 1985 Oct-Dec;89(4):597-601.
7
Cushing's syndrome produced by a bronchial carcinoid tumor.
Hum Pathol. 1984 Sep;15(9):890-2. doi: 10.1016/s0046-8177(84)80151-3.
8
Cushing's syndrome due to ACTH-production of an ovarian carcinoid.由卵巢类癌产生促肾上腺皮质激素(ACTH)所致的库欣综合征。
Klin Wochenschr. 1989 Jun 15;67(12):640-4. doi: 10.1007/BF01718148.
9
Adrenocorticotropin-secreting carcinoid tumour identified and treated 12 years after presentation with Cushing's syndrome.分泌促肾上腺皮质激素的类癌肿瘤在库欣综合征出现12年后得以确诊并接受治疗。
Postgrad Med J. 1997 Nov;73(865):737-9. doi: 10.1136/pgmj.73.865.737.
10
[Cushing's syndrome quick installation].
Rev Prat. 2014 Sep;64(7):904.

引用本文的文献

1
Cushing's syndrome due to ACTH-production of an ovarian carcinoid.由卵巢类癌产生促肾上腺皮质激素(ACTH)所致的库欣综合征。
Klin Wochenschr. 1989 Jun 15;67(12):640-4. doi: 10.1007/BF01718148.

本文引用的文献

1
Cause of Cushing's syndrome in patients with tumors arising from "nonendocrine" tissue.“非内分泌”组织来源肿瘤患者库欣综合征的病因
J Clin Endocrinol Metab. 1962 Jul;22:693-703. doi: 10.1210/jcem-22-7-693.
2
HUMORAL SYNDROMES ASSOCIATED WITH NONENDOCRINE TUMORS.
Ann Intern Med. 1964 Oct;61:733-56. doi: 10.7326/0003-4819-61-4-733.
3
MULTIPLE BRONCHIAL ADENOMAS, CUSHING'S SYNDROME AND HYPOKALEMIC ALKALOSIS. REPORT OF A CASE.多发性支气管腺瘤、库欣综合征与低钾性碱中毒。病例报告。
Dis Chest. 1964 Sep;46:367-71. doi: 10.1378/chest.46.3.367.
4
NEOPLASMS OF BRONCHUS COMMONLY DESIGNATED AS ADENOMAS.通常被称为腺瘤的支气管肿瘤。
Cancer. 1964 May;17:590-608. doi: 10.1002/1097-0142(196405)17:5<590::aid-cncr2820170508>3.0.co;2-j.
5
ADRENOCORTICAL HYPERFUNCTION AND POTASSIUM METABOLISM IN PATIENTS WITH "NON- ENDOCRINE" TUMORS AND CUSHING'S SYNDROME.“非内分泌”肿瘤和库欣综合征患者的肾上腺皮质功能亢进与钾代谢
J Clin Endocrinol Metab. 1963 Aug;23:737-46. doi: 10.1210/jcem-23-8-737.
6
Bronchial adenomas in Cushing's syndrome: their relation to thymomas and oat cell carcinomas associated with hyperadrenocorticism.库欣综合征中的支气管腺瘤:它们与伴有肾上腺皮质功能亢进的胸腺瘤和燕麦细胞癌的关系。
Cancer. 1960 Jul-Aug;13:812-7. doi: 10.1002/1097-0142(196007/08)13:4<812::aid-cncr2820130425>3.0.co;2-u.
7
Functioning malignant bronchial carcinoid with Cushing's syndrome and recurrent sinus arrest.
Ann Intern Med. 1961 Jun;54:1248-59. doi: 10.7326/0003-4819-54-6-1248.
8
Adrenocorticotrophic activity in the plasma of patients with Cushing's syndrome associated with pulmonary neoplasms.与肺部肿瘤相关的库欣综合征患者血浆中的促肾上腺皮质激素活性。
Lancet. 1961 Jan 14;1(7168):85-6. doi: 10.1016/s0140-6736(61)92125-0.
9
The natural history of Cushing's syndrome.库欣综合征的自然病史。
Am J Med. 1952 Nov;13(5):597-614. doi: 10.1016/0002-9343(52)90027-2.
10
[Cushing's syndrome in bronchial carcinoid: suppressible ectopic ACTH selection].[支气管类癌中的库欣综合征:可抑制性异位促肾上腺皮质激素分泌型]
Schweiz Med Wochenschr. 1982 Oct 23;112(43):1507-14.