小腿围度可作为预测肝病患者肌肉减少症的有用指标。
Calf Circumference as a Useful Predictor of Sarcopenia in Patients With Liver Diseases.
机构信息
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Hyogo College of Medicine, Nishinomiya, Japan
Center for Clinical Research and Education, Hyogo College of Medicine, Nishinomiya, Japan.
出版信息
In Vivo. 2020 Sep-Oct;34(5):2561-2569. doi: 10.21873/invivo.12073.
BACKGROUND/AIM: To elucidate the influence of calf circumference (CC) on sarcopenia in patients with chronic liver damages (CLDs, n=525, 255 men).
PATIENTS AND METHODS
Anthropometry parameters including arm circumference, arm muscle circumference, CC, arm muscle area, triceps skinfold thickness, waist circumference and body mass index were measured. Patients with both grip strength (GS) decline and skeletal muscle index (SMI) decline were diagnosed as sarcopenic.
RESULTS
Liver cirrhosis was identified in 103 cases (40.4%) in males and 87 cases (32.2%) in females. Sarcopenia was identified in 23 male patients (9.0%) and 38 female patients (14.1%). CC had the strong positive correlation with SMI both in male (r=0.79, p<0.0001) and female (r=0.83, p<0.0001). Among the above mentioned 7 anthropometry parameters, CC had the highest area under the receiver operating characteristics curve (AUC) for sarcopenia both in males (AUC=0.88) and females (AUC=0.86).
CONCLUSION
CC can be helpful for predicting sarcopenia in CLDs.
背景/目的：阐明小腿围（CC）对慢性肝损伤（CLD，n=525，255 名男性）患者肌少症的影响。
患者和方法
测量人体测量参数，包括臂围、臂肌围、CC、臂肌面积、肱三头肌皮褶厚度、腰围和体重指数。握力（GS）和骨骼肌指数（SMI）均下降的患者被诊断为肌少症。
结果
在男性中，103 例（40.4%）患者为肝硬化，87 例（32.2%）患者为女性。23 名男性患者（9.0%）和 38 名女性患者（14.1%）患有肌少症。CC 与男性（r=0.79，p<0.0001）和女性（r=0.83，p<0.0001）的 SMI 均呈强正相关。在上述 7 个人体测量参数中，CC 对男性（AUC=0.88）和女性（AUC=0.86）肌少症的受试者工作特征曲线下面积（AUC）最高。
结论
CC 有助于预测 CLD 患者的肌少症。
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