利用易位染色体分析对人类c-rel基因座进行区域定位。
Regional localization of the human c-rel locus using translocation chromosome analysis.
作者信息
Brownell E, Fell H P, Tucker P W, Geurts van Kessel A H, Hagemeijer A, Rice N R
机构信息
Bri-Basic Research Program, NCI-Frederick Cancer Research Facility, Maryland 21701.
出版信息
Oncogene. 1988 May;2(5):527-9.
PMID:3287280
Abstract
The human cellular homolog of v-rel, the transforming gene of reticuloendotheliosis virus, strain T, was previously localized to 2 cent-2p13 by a combination of somatic cell hybrid and in situ hybridization analyses. In this study, we use translocation chromosome analysis to refine c-rel's genetic assignment to 2p12-2p13.
摘要
网状内皮组织增生症病毒T株的转化基因v-rel的人类细胞同源物，先前通过体细胞杂交和原位杂交分析相结合的方法定位到2号染色体短臂2区带2p13。在本研究中，我们利用易位染色体分析将c-rel的基因定位精确到2p12-2p13。
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