度洛西汀致 2 型糖尿病伴糖尿病神经病变患者高血压急症。
Duloxetine-induced hypertensive urgency in type 2 diabetes mellitus with diabetic neuropathy.
机构信息
Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Department of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
出版信息
Indian J Pharmacol. 2020 May-Jun;52(3):213-215. doi: 10.4103/ijp.IJP_370_19. Epub 2020 Aug 4.
We present a case of hypertensive urgency in a diabetic patient with painful diabetic neuropathy on duloxetine treatment. The patient's blood pressure was high after taking 1-day dose of duloxetine and the patient was diagnosed with hypertensive urgency. The patient was managed with labetalol, leading to reduction in blood pressure. The patient's medication was switched to telmisartan and metoprolol, which leads to resolution of increased blood pressure. This case report is a possible case of hypertensive urgency after the initiation of duloxetine managed with antihypertensives and resolves with the discontinuation of the duloxetine.
我们报告了 1 例糖尿病患者伴有痛性糖尿病周围神经病变，在服用度洛西汀后出现血压急骤升高，诊断为高血压急症。给予拉贝洛尔降压治疗后血压下降。后将药物更换为替米沙坦和倍他洛尔，血压恢复正常。该病例提示在起始度洛西汀治疗后可能发生高血压急症，经降压治疗后停用度洛西汀可使血压恢复正常。
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