[弥散性血管内凝血：国际血栓与止血协会（ISTH）诊断评分系统的作用]
[Disseminated intravascular coagulation: role of the International Society on Thrombosis and Haemostasis (ISTH) diagnostic scoring system].
作者信息
Bouzidi Sawsen, Daiki Mayssa, Nasr Amen Allah, Nsiri Kaouther, Layouni Samy, Hajjej Zied, Fekih-Mrissa Najiba, Ferjani Mustapha, Nsiri Brahim
机构信息
Laboratoire d´Hématologie, Hôpital Militaire Principal d´Instruction de Tunis, Tunis, Tunisie.
Service d´Anesthésie Réanimation, Hôpital Militaire Principal d´Instruction de Tunis, Tunis, Tunisie.
出版信息
Pan Afr Med J. 2020 Jul 6;36:154. doi: 10.11604/pamj.2020.36.154.20368. eCollection 2020.
Disseminated intravascular coagulation (DIC) is a life-threatening event during resuscitation. The International Society on Thrombosis and Haemostasis (ISTH) diagnostic scoring system enables early diagnosis of DIC. We here report three clinical cases of DIC characterized by several etiologies: prostatic adenocarcinoma, septic shock and retroplacental hematoma. The tests of hemostasis needed to calculate international society on thrombosis and haemostasis (ISTH) score (platelet count, prothrombin ratio, values of fibrinogen and D-dimer levels) were performed regularly. Additional, complementary tests (soluble complexes test, euglobulin lysis test, antithrombin level dosing, activated protein C and factor V dosing) were also performed. ISTH score enables early diagnosis of DIC.
弥散性血管内凝血（DIC）是复苏过程中危及生命的事件。国际血栓与止血学会（ISTH）诊断评分系统能够早期诊断DIC。我们在此报告三例DIC临床病例，其病因多样：前列腺腺癌、感染性休克和胎盘后血肿。定期进行计算国际血栓与止血学会（ISTH）评分所需的止血检查（血小板计数、凝血酶原比率、纤维蛋白原值和D - 二聚体水平）。此外，还进行了补充检查（可溶性复合物试验、优球蛋白溶解试验、抗凝血酶水平测定、活化蛋白C和因子V测定）。ISTH评分能够早期诊断DIC。
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