Dourra Mohsen, Mussad Shiab, Singer Robert
Medicine, Michigan State University, East Lansing, USA.
Dermatology, Ascension Providence Hospital Southfield Campus, Southfield, USA.
Cureus. 2020 Aug 27;12(8):e10089. doi: 10.7759/cureus.10089.
Hemophagocytic lymphohistiocytosis (HLH) is a rare hematologic disease caused by a disordered immune system. We present a case of reactive HLH (RHLH) with uncommon skin findings in a 35-year-old African American female with a history of hidradenitis suppurativa and morbid obesity. Skin findings on physical exam revealed bullous, ecchymotic, hypopigmented, and ulcerated lesions. The literature on the cutaneous lesions of RHLH is limited. Skin findings are an underrecognized feature of RHLH and can help alert to its presence or its recurrence after treatment.
噬血细胞性淋巴组织细胞增生症（HLH）是一种由免疫系统紊乱引起的罕见血液疾病。我们报告一例反应性HLH（RHLH）病例，该病例为一名35岁非裔美国女性，有化脓性汗腺炎和病态肥胖史，其皮肤表现罕见。体格检查发现的皮肤表现为水疱、瘀斑、色素减退和溃疡病变。关于RHLH皮肤病变的文献有限。皮肤表现是RHLH一个未被充分认识的特征，有助于提示其存在或治疗后复发。
