Wu Zeng-Jie, Bian Tian-Tian, Zhan Xiao-Hong, Dong Cheng, Wang Yan-Li, Xu Wen-Jian
Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China.
Breast Disease Center, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China.
World J Clin Cases. 2020 Aug 6;8(15):3349-3354. doi: 10.12998/wjcc.v8.i15.3349.
Alveolar soft part sarcoma (ASPS) is an extremely rare malignant sarcoma, accounting for less than 1% of all soft-tissue sarcomas. However, limited information is available on multimodal imaging [computed tomography (CT), magnetic resonance imaging (MRI), and positron emission computed tomography/computed tomography (PET/CT)] of ASPS.
This study reports a case of a 35-year-old female patient with ASPS of the left thigh with lung metastasis. The patient presented with a 1-year history of a palpable mass in the lower extremity, which exhibited rapid growth for 3 wk. CT, MRI, and F-deoxyglucose PET/CT examinations were performed. CT showed a slightly hypodense or isodense mass with patchy calcifications. On MRI examination, the mass manifested hyperintensity on T1-weighted, T2-weighted, and diffusion-weighted images with some signal voids. PET/CT images demonstrated an intensely hypermetabolic mass in the left thigh and hypermetabolic nodules in lungs.
ASPS should be considered as a possible diagnosis when a slow-growing mass is detected in the soft tissue of the extremities, with hyperintensity and numerous signal voids on T1-weighted, T2-weighted, and diffusion-weighted images and intense F-deoxyglucose uptake on PET/CT. ASPS can have calcifications on CT.
肺泡软组织肉瘤(ASPS)是一种极其罕见的恶性肉瘤,占所有软组织肉瘤的比例不到1%。然而,关于ASPS的多模态成像[计算机断层扫描(CT)、磁共振成像(MRI)和正电子发射计算机断层扫描/计算机断层扫描(PET/CT)]的信息有限。
本研究报告1例35岁左大腿ASPS伴肺转移的女性患者。患者下肢出现可触及肿块1年,肿块在3周内迅速生长。进行了CT、MRI和F-脱氧葡萄糖PET/CT检查。CT显示肿块呈稍低密度或等密度,伴有斑片状钙化。MRI检查显示,肿块在T1加权、T2加权和扩散加权图像上呈高信号,有一些信号缺失。PET/CT图像显示左大腿有一高代谢肿块,肺部有高代谢结节。
当在四肢软组织中检测到生长缓慢的肿块,在T1加权、T2加权和扩散加权图像上呈高信号且有大量信号缺失,在PET/CT上有强烈的F-脱氧葡萄糖摄取时,应考虑ASPS的可能诊断。ASPS在CT上可出现钙化。