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对抗阿片类药物流行:全关节置换术单一处方的经验

Combating the Opioid Epidemic: Experience with a Single Prescription for Total Joint Arthroplasty.

作者信息

Sun Daniel, Cusano Antonio, Harrington Melvin A, Halawi Mohamad J

机构信息

Department of Orthopaedic Surgery, Baylor College of Medicine, Houston, TX, USA.

Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT, USA.

出版信息

Arthroplast Today. 2020 Aug 23;6(4):668-671. doi: 10.1016/j.artd.2020.07.013. eCollection 2020 Dec.

Abstract

BACKGROUND

Despite advances in perioperative total joint arthroplasty (TJA) pain protocols, opiates continue to play a major role in postoperative pain control. This brief communication reports our experience with a restrictive opioid protocol allowing patients only a single prescription of low-dose opioids.

METHODS

One hundred consecutive elective, primary, and revision TJAs were analyzed. All patients received preoperative counseling and multimodal analgesia. Counseling involved discussion of patient expectations on postoperative pain management, weaning off opioids before surgery, and emphasis that opioid refills were not permitted. Ninety-day outcomes including pain-related phone calls, opioid refill requests, emergency room visits, complications, and readmissions were assessed. Opioid dispensing was tracked using our state prescription monitoring program.

RESULTS

There was a high prevalence of preoperative opioid use, depression, and anxiety (25%, 34%, and 39%, respectively). Sixty-eight percent of chronic opioid users were able to wean off opioids before surgery. The average initial prescription of opioids was equivalent to 48 pills of 5 mg oxycodone. There were only 10 pain-related phone calls from 9 patients; all were using opioids preoperatively, with only one patient requesting a refill. All pain-related phone calls occurred in the first week after surgery. There were no emergency room visits, complications, or readmissions related to pain.

CONCLUSIONS

A single prescription of low-dose opioids was sufficient for patients undergoing TJA when using preoperative patient preparation and multimodal analgesia. Standardized guidelines are needed to guide best practices for patient education and pain management, especially in patients on chronic opioid therapy. This information will help implement evidence-based strategies to accelerate the decline of opioid use and hopefully pave the way for opioid-free TJA.

摘要

背景

尽管围手术期全关节置换术(TJA)疼痛方案有所进展,但阿片类药物在术后疼痛控制中仍发挥着重要作用。本简短通讯报告了我们采用限制性阿片类药物方案的经验,该方案仅允许患者开具一次低剂量阿片类药物处方。

方法

对连续100例择期、初次及翻修TJA病例进行分析。所有患者均接受术前咨询和多模式镇痛。咨询内容包括讨论患者对术后疼痛管理的期望、术前停用阿片类药物,并强调不允许补充阿片类药物。评估90天的结果,包括与疼痛相关的电话、阿片类药物补充请求、急诊就诊、并发症和再入院情况。使用我们州的处方监测程序跟踪阿片类药物的配药情况。

结果

术前使用阿片类药物、抑郁和焦虑的发生率较高(分别为25%、34%和39%)。68%的慢性阿片类药物使用者能够在术前停用阿片类药物。阿片类药物的平均初始处方量相当于48片5毫克羟考酮。9名患者仅拨打了10次与疼痛相关的电话;所有患者术前均使用阿片类药物,只有1名患者请求补充药物。所有与疼痛相关的电话均发生在术后第一周。没有与疼痛相关的急诊就诊、并发症或再入院情况。

结论

在使用术前患者准备和多模式镇痛时,单次低剂量阿片类药物处方对接受TJA的患者就足够了。需要标准化指南来指导患者教育和疼痛管理的最佳实践,尤其是对接受慢性阿片类药物治疗的患者。这些信息将有助于实施基于证据的策略,以加速阿片类药物使用的下降,并有望为无阿片类药物TJA铺平道路。

相似文献

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Preoperative Reduction of Opioid Use Before Total Joint Arthroplasty.全关节置换术前减少阿片类药物使用量
J Arthroplasty. 2016 Sep;31(9 Suppl):282-7. doi: 10.1016/j.arth.2016.01.068. Epub 2016 Mar 17.

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