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[老年股骨颈骨折患者半髋关节置换术直接前路与其他入路的Meta分析]

[Meta-analysis of direct anterior approach and other approaches for hemiarthroplasty in elderly patients with femoral neck fracture].

作者信息

Zhang Jia-Kai, Wu Jun-Long, Zheng Xing-Guo, Zhu Hui-Min, Pang Qing-Jiang

机构信息

Department of Orthopaedics, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo 315010, Zhejiang, China.

出版信息

Zhongguo Gu Shang. 2020 Aug 25;33(8):776-83. doi: 10.12200/j.issn.1003-0034.2020.08.018.

Abstract

OBJECTIVE

To systematically evaluate the clinical efficacy of high-quality direct anterior approach (DAA) and other approaches for the treatment of elderly patients with femoral neck fracture.

METHODS

Literatures published in English or Chinese about the direct anterior approach and other approaches for hemiarthroplasty in femoral neck fracture were searched on Cochrane Library, PubMed, EMBASE, Web of science, Wanfang, CNKI databases from their establishment to May 2019. According to the inclusion and exclusion criteria, two researchers independently screened the literatures, and extracted the data. The quality of RCT were evaluated by Cochrane Risk of Bias Assessment Tool, and non-RCT were evaluated by the NOS scale. Meta-analysis was performed using the RevMan 5.3 software.

RESULTS

A total of 9 articles were included with 901 cases, in which 429 cases used DAA, and 472 used other approaches. DAA had a significantly lower dislocation rate compared to subgroup of posterior and posterolateral approach [=0.19, 95%CI (0.06, 0.61), =0.005]. No significant differences were found between DAA group and subgroup of direct lateral and anterolateral approach[=1.08, 95%CI(0.20, 5.76), =0.93]. Also there were no relevant differences between the DAA group and control in infection rate[=1.07, 95%CI(0.47, 2.43), =0.88], perioperative fracture rate[=0.95, 95%CI(0.36, 2.50), =0.92], re operation rate[=0.76, 95%CI(0.30, 1.89), =0.55], overall complication rate [=0.88, 95%CI (0.63, 1.22), =0.44], mortality [=1.33, 95%CI (0.84, 2.11), =0.23], operative time[MD=1.43, 95%CI(-5.85, 8.71), =0.70].

CONCLUSION

The current evidenceindicates that the DAA was associated with a significantly lower dislocation rate compared to posterior capsular approaches for hemiarthroplasty. There was no significant difference in dislocation rate with the lateral and anterolateral approach.

摘要

目的

系统评价高质量直接前路(DAA)与其他手术入路治疗老年股骨颈骨折的临床疗效。

方法

在Cochrane图书馆、PubMed、EMBASE、Web of science、万方、知网数据库中检索自建库至2019年5月发表的关于股骨颈骨折半髋关节置换术的直接前路及其他手术入路的英文或中文文献。根据纳入和排除标准,两名研究者独立筛选文献并提取数据。采用Cochrane偏倚风险评估工具对随机对照试验(RCT)的质量进行评估,采用NOS量表对非RCT进行评估。使用RevMan 5.3软件进行Meta分析。

结果

共纳入9篇文献,901例患者,其中429例采用DAA,472例采用其他手术入路。与后入路和后外侧入路亚组相比,DAA的脱位率显著更低[比值比(OR)=0.19,95%可信区间(CI)(0.06,0.61),P=0.005]。DAA组与直接外侧入路和前外侧入路亚组之间未发现显著差异[OR=1.08,95%CI(0.20,5.76),P=0.93]。DAA组与对照组在感染率[OR=1.07,95%CI(0.47,2.43),P=0.88]、围手术期骨折率[OR=0.95,95%CI(0.36,2.50),P=0.92]、再次手术率[OR=0.76,95%CI(0.30,1.89),P=0.55]、总体并发症发生率[OR=0.88,95%CI(0.63,1.22),P=0.44]、死亡率[OR=1.33,95%CI(0.84,2.11),P=0.23]、手术时间[平均差(MD)=1.43,95%CI(-5.85,8.71),P=0.70]方面也未发现相关差异。

结论

目前证据表明,与半髋关节置换术的后囊入路相比,DAA的脱位率显著更低。与外侧和前外侧入路相比,脱位率无显著差异。

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