Ang Bryan, Lafage Renaud, Elysée Jonathan Charles, Pannu Tejbir S, Bannwarth Mathieu, Carlson Brandon B, Schwab Frank J, Kim Han Jo, Lafage Virginie
25062Hospital for Special Surgery, New York, NY, USA.
Weill Cornell Medicine Medical School, New York, NY, USA.
Global Spine J. 2021 May;11(4):541-548. doi: 10.1177/2192568220914882. Epub 2020 Apr 1.
Retrospective single-center study.
Investigate the effect of posterior instrumentation on the relationship between lordosis and kyphosis.
Surgically treated patients with a minimum of 6 months of follow-up were analyzed. Asymptomatic volunteers served to show the normal anatomical relationship between thoracic and lumbar curves. Patients were stratified based on postoperative instrumentation: "Thoracic Fusion" = complete fusion of thoracic spine; "Lumbar Fusion" = complete fusion of lumbar spine; and "Complete Fusion" = fusion from sacrum to at least T5. Bivariate correlations and regression analysis were used to evaluate the relationship between change in thoracic kyphosis (ΔTK) and change in spinopelvic mismatch (ΔPI-LL; pelvic incidence-lumbar lordosis) before and after fusion. Analyses were repeated in "Lumbar Fusion" patients with flexible preoperative thoracic spines.
For asymptomatic volunteers, the natural anatomical relationship between TK and LL was found to be TK = 41% of LL ( = 0.425, < .001). A total of 153 of 167 adult spinal deformity patients were included (62 years old, 26.7 kg/m, 78% female). Mean follow-up was 11.5 ± 6.8 months. "Thoracic Fusion" group showed no alteration in the natural relationship between TK and LL (ΔTK = 39% ΔPI-LL), whereas "Lumbar Fusion" group had a reduction in reciprocal change (ΔTK = 34% ΔPI-LL) although a subanalysis of patients in the "Lumbar Fusion" group with flexible thoracic spines showed a marked compensation in reciprocal change with (ΔTK = 58% ΔPI-LL).
The relationship between ΔTK and ΔPI-LL is dependent on level instrumented. "Thoracic Fusion" drives change in LL while this relationship is affected by TK's natural stiffness in "Lumbar Fusion" patients.
回顾性单中心研究。
研究后路内固定对前凸和后凸关系的影响。
分析至少随访6个月的手术治疗患者。无症状志愿者用于展示胸腰段曲线的正常解剖关系。根据术后内固定情况对患者进行分层:“胸椎融合”=胸椎完全融合;“腰椎融合”=腰椎完全融合;“完全融合”=从骶骨至至少T5融合。采用双变量相关性和回归分析评估融合前后胸段后凸变化(ΔTK)与脊柱骨盆失配变化(ΔPI-LL;骨盆入射角-腰椎前凸)之间的关系。对术前胸椎灵活的“腰椎融合”患者重复进行分析。
对于无症状志愿者,发现TK与LL的自然解剖关系为TK = LL的41%( = 0.425, <.001)。167例成人脊柱畸形患者中共有153例纳入研究(年龄62岁,体重指数26.7 kg/m,78%为女性)。平均随访时间为11.5±6.8个月。“胸椎融合”组中TK与LL的自然关系无改变(ΔTK = 39% ΔPI-LL),而“腰椎融合”组的相互变化有所减少(ΔTK = 34% ΔPI-LL),尽管对“腰椎融合”组中胸椎灵活的患者进行亚分析显示相互变化有明显代偿(ΔTK = 58% ΔPI-LL)。
ΔTK与ΔPI-LL之间的关系取决于内固定的节段。“胸椎融合”促使LL发生改变,而在“腰椎融合”患者中这种关系受TK自然硬度的影响。