Gallino A, Eugster W, Schneider K, Furrer M, Turina M
Medizinische Klinik, Universitätsspital Zürich.
Schweiz Med Wochenschr. 1988 Apr 9;118(14):522-4.
Indication and contraindications for selection of patients for cardiac transplantation are given on the basis of 2 years' experience in evaluating a total of 65 patients, 30 of whom received heart transplant. Heart transplant must be considered in patients with: 1. Severe heart failure without response to maximal medical treatment. 2. End stage coronary artery disease where clinical heart surgery is no longer feasible. 3. Intractable malignant arrhythmia associated with pump failure. Heart transplant is contraindicated in: 1. Patients with extracardiac polymorbidity. 2. Cardiac low output with renal and hepatic impairment. 3. Compliance failure. 4. Increased pulmonary artery resistance. 5. Age over 60 years.
根据对总共65例患者进行评估的2年经验，给出了心脏移植患者选择的适应证和禁忌证，其中30例接受了心脏移植。对于以下患者必须考虑心脏移植：1. 严重心力衰竭，对最大程度的药物治疗无反应。2. 终末期冠状动脉疾病，临床心脏手术不再可行。3. 与泵衰竭相关的顽固性恶性心律失常。心脏移植的禁忌证包括：1. 伴有心外多种疾病的患者。2. 伴有肾和肝损害的心脏低输出量。3. 依从性差。4. 肺动脉阻力增加。5. 年龄超过60岁。
