颅骨溶骨性病变：慢性肉芽肿病的一种罕见表现。
Lytic lesion of skull: a rare presentation of chronic granulomatous disease.
机构信息
Pediatrics, Case Western Reserve University Hospital, Cleveland, Ohio, USA
出版信息
BMJ Case Rep. 2020 Sep 2;13(9):e235423. doi: 10.1136/bcr-2020-235423.
Abstract
An 18-month-old boy presented with lytic lesion of skull and recurrent abscesses with The extensive work up revealed a gene mutation confirming the diagnosis of chronic granulomatous disease (CGD). This case scenario underscores the importance of exploring the possibility of immunodeficiency if there is a history of recurrent abscesses with atypical organism. The case also demonstrates that CGD can present as lytic lesion of skull.
摘要
一名 18 个月大的男童出现颅骨溶骨性病变和复发性脓肿，广泛的检查显示基因突变，确诊为慢性肉芽肿病（CGD）。如果有复发性脓肿伴非典型病原体的病史，这种情况下就需要探索免疫缺陷的可能性。本病例还表明，CGD 可表现为颅骨溶骨性病变。
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Serratia marcescens osteomyelitis in a newborn with chronic granulomatous disease.
Pediatr Infect Dis J. 2013 Aug;32(8):926. doi: 10.1097/INF.0b013e31828f682a.
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