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可调胃束带转换为 Roux-en-Y 胃旁路术:一步法还是两步法?最佳方法是什么?一项涉及 832 例患者的多中心数据库分析。

Conversion of Adjustable Gastric Banding to Roux-en-Y Gastric Bypass in One or Two Steps: What Is the Best Approach? Analysis of a Multicenter Database Concerning 832 Patients.

机构信息

Clínica Mi Tres Torres, Barcelona, Spain.

American University of Beirut Medical Center (AUBMC), Beirut, Lebanon.

出版信息

Obes Surg. 2020 Dec;30(12):5026-5032. doi: 10.1007/s11695-020-04951-0. Epub 2020 Sep 3.

Abstract

BACKGROUND

Roux-en-Y gastric bypass (RYGB) is often the preferred conversion procedure for laparoscopic adjustable gastric banding (LAGB) poor responders. However, there is controversy whether it is better to convert in one or two stages. This study aims to compare the outcomes of one and two-stage conversions of LAGB to RYGB.

METHODS

Retrospective review of a multicenter prospectively collected database. Data on conversion in one and two stages was compared.

RESULTS

Eight hundred thirty-two patients underwent LAGB conversion to RYGB in seven specialized bariatric centers. Six hundred seventy-three (81%) were converted in one-stage. Patients in the two-stage group were more likely to have experienced technical complications, such as slippage or erosions (86% vs. 37%, p = 0.0001) and to have had a higher body mass index (BMI) (41.6 vs. 39.9 Kg/m, p = 0.005). There were no differences in postoperative complications and mortality rates between the one-stage and two-stage groups (13.5% vs. 10.8%, and 0.7% vs. 0.0% respectively, p = ns). Mean final BMI and %total weight loss (%TWL) for the one-stage and the two-stage groups were 31.6 vs. 32.4 Kg/m (p = ns) and 30.4 vs. 26.8 (p = 0.017) after a mean follow-up of 33 months. Follow-up at 1, 3, and 5 years was 98%, 75%, and 54%, respectively.

CONCLUSIONS

One-stage conversion of LAGB to RYGB is safe and effective. Two-stage conversion carries low morbidity and mortality in the case of band slippage, erosion, or higher BMI patients. These findings suggest the importance of patient selection when choosing the appropriate conversion approach.

摘要

背景

Roux-en-Y 胃旁路术(RYGB)通常是腹腔镜可调胃束带术(LAGB)治疗效果不佳患者的首选转换术式。然而,对于是否应该分阶段进行转换仍存在争议。本研究旨在比较 LAGB 到 RYGB 的一次性和分阶段转换的结果。

方法

回顾性分析七个专门的减肥中心前瞻性收集的多中心数据库。比较了一次性和分阶段转换的数据。

结果

832 例患者在七个专门的减肥中心接受了 LAGB 到 RYGB 的转换。其中 673 例(81%)患者进行了一次性转换。分阶段组的患者更有可能经历技术并发症,如滑脱或侵蚀(86%比 37%,p=0.0001),并且体重指数(BMI)更高(41.6 比 39.9 Kg/m,p=0.005)。一次性和分阶段组的术后并发症和死亡率无差异(分别为 13.5%比 10.8%,和 0.7%比 0.0%,p=ns)。一次性和分阶段组的最终 BMI 和总体重减轻百分比(%TWL)分别为 31.6 比 32.4 Kg/m(p=ns)和 30.4 比 26.8(p=0.017),随访时间平均为 33 个月。1、3 和 5 年的随访率分别为 98%、75%和 54%。

结论

LAGB 到 RYGB 的一次性转换是安全有效的。对于胃带滑脱、侵蚀或 BMI 较高的患者,分阶段转换的发病率和死亡率较低。这些发现表明,在选择适当的转换方法时,患者选择很重要。

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