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腹腔镜胃带术失败后再次减重手术的一步法:一项具有 2 年随访的回顾性队列研究。

Revisional One-Step Bariatric Surgical Techniques After Unsuccessful Laparoscopic Gastric Band: A Retrospective Cohort Study with 2-Year Follow-up.

机构信息

Department of Surgery, Medical Research Institute, Alexandria University, 165 Horreya Avenue, Hadara, Alexandria, 21561, Egypt.

Consultant of Bariatric Surgery at Madina Women's Hospital, Alexandria, Egypt.

出版信息

Obes Surg. 2024 Mar;34(3):814-829. doi: 10.1007/s11695-023-07039-7. Epub 2024 Jan 17.

Abstract

BACKGROUND

Laparoscopic adjustable gastric banding (LAGB) has high reported rates of revision due to poor weight loss (WL) and high complication rates. Yet, there is yet to be a consensus on the best revisional procedure after unsuccessful LAGB, and studies comparing different revisional procedures after LAGB are still needed.

METHODS

This was a retrospective cohort study that compared the outcomes of one-step revisional Roux-en-Y gastric bypass (rRYGB), one-anastomosis gastric bypass (rOAGB), or laparoscopic sleeve gastrectomy (rLSG) after LAGB. WL, complications, resolution of associated medical conditions, and food tolerance were assessed with a post hoc pairwise comparison one-way analysis of variance (ANOVA) throughout a 2-year follow-up.

RESULTS

The final analysis included 102 (rRYGB), 80 (rOAGB), and 70 (rLSG) patients. After 2 years, an equal percentage of excess weight loss was observed in rOAGB and rRYGB (both >90%; p=0.998), significantly higher than that in rLSG (83.6%; p<0.001). In our study, no leaks were observed. rRYGB had higher complication rates according to the Clavien-Dindo classification (10.8% vs. 3.75% and 5.7% in rOAGB and rLSG, respectively, p=0.754), and re-operations were not statistically significant. Food tolerance was comparable between rOAGB and rRYGB (p = 0.987), and both had significantly better food tolerance than rLSG (p<0.001). The study cohorts had comparable resolution rates for associated medical problems (p>0.60).

CONCLUSION

rOAGB and rRYGB had better outcomes after LAGB than rLSG regarding WL, feasibility, food tolerance, and safety. rOAGB had significantly higher rates of nutritional deficiencies.

摘要

背景

腹腔镜可调节胃束带术(LAGB)因减重效果不佳和并发症发生率高而有较高的报道修正率。然而,对于 LAGB 失败后的最佳修正程序仍未达成共识,仍需要研究比较 LAGB 后的不同修正程序。

方法

这是一项回顾性队列研究,比较了 LAGB 后一步式 Roux-en-Y 胃旁路术(rRYGB)、单吻合口胃旁路术(rOAGB)或腹腔镜袖状胃切除术(rLSG)的结果。在 2 年的随访中,使用事后两两比较的单向方差分析(ANOVA)评估体重减轻(WL)、并发症、相关医疗状况的解决情况和食物耐受性。

结果

最终分析包括 102 例(rRYGB)、80 例(rOAGB)和 70 例(rLSG)患者。2 年后,rOAGB 和 rRYGB 的多余体重减轻百分比相等(均>90%;p=0.998),明显高于 rLSG(83.6%;p<0.001)。在我们的研究中,没有观察到漏诊。rRYGB 根据 Clavien-Dindo 分类的并发症发生率更高(10.8%比 rOAGB 和 rLSG 的 3.75%和 5.7%,p=0.754),且再手术无统计学意义。rOAGB 和 rRYGB 的食物耐受性相当(p = 0.987),且两者均显著优于 rLSG(p<0.001)。研究队列的相关医疗问题解决率相当(p>0.60)。

结论

rOAGB 和 rRYGB 在 WL、可行性、食物耐受性和安全性方面比 rLSG 更适合 LAGB 后的修正。rOAGB 有显著更高的营养缺乏发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9455/10899297/b9d93afe5c04/11695_2023_7039_Fig1_HTML.jpg

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