Romailler Élodie, Schmidt Kobbe Sabine, Moradpour Darius, Sempoux Christine
Service de gastroentérologie et d'hépatologie, CHUV et Université de Lausanne, 1011 Lausanne.
Service de radiodiagnostic et radiologie interventionnelle, CHUV et Université de Lausanne, 1011 Lausanne.
Rev Med Suisse. 2020 Sep 2;16(704):1554-1559.
Hepatocellular adenomas (HA) are rare benign liver tumors known to affect mainly women of reproductive age taking oral contraception. They can be complicated by hemorrhage or malignant transformation to hepatocellular carcinoma, especially when the size of the lesion exceeds 5 cm. Magnetic resonance imaging is the most specific tool for the non-invasive characterization of HA. The discovery of mutations underlying different specific HA phenotypes has allowed the establishment of a molecular classification that modified the management of this pathology.
肝细胞腺瘤（HA）是一种罕见的良性肝脏肿瘤，主要影响服用口服避孕药的育龄女性。它们可能会并发出血或恶变成为肝细胞癌，尤其是当病变大小超过5厘米时。磁共振成像（MRI）是对HA进行非侵入性特征描述的最具特异性的工具。不同特定HA表型潜在突变的发现，使得建立一种分子分类成为可能，这种分类改变了对该疾病的治疗方法。
