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配偶因自杀而丧亲:基于人群的纵向队列比较研究,比较了医生诊断的精神障碍和住院自杀未遂。

Spouses bereaved by suicide: A population-based longitudinal cohort comparison of physician-diagnosed mental disorders and hospitalized suicide attempts.

机构信息

Department of Community Health Sciences, Department of Psychiatry, University of Manitoba, Canada.

Community Health Sciences, University of Manitoba, S101D-750 Bannatyne Avenue, Winnipeg, MB, R3E 0W3, Canada.

出版信息

J Psychiatr Res. 2020 Nov;130:347-354. doi: 10.1016/j.jpsychires.2020.07.028. Epub 2020 Aug 8.

Abstract

BACKGROUND

This study compares a longitudinal population-based sample of spouses bereaved by suicide and those bereaved by other sudden deaths to determine if suicide-bereaved spouses (SBS) experience greater rates of physician-diagnosed mental disorders.

METHODS

First, married individuals whose spouse died by suicide, sudden natural death (SND) and unintentional injury (UI) were compared to non-bereaved matched cohorts to determine if there were differences in mental disorder rates between bereavement groups and non-bereaved matches. Second, SBS (n = 365), spouses bereaved by SND (n = 1000), and spouses bereaved by UI (n = 270), were compared using inverse probability treatment weighting and generalized estimating equations to calculate relative rates of mental disorders 5 years before/after death.

OUTCOMES

All bereaved cohorts had higher rates of mental disorders compared to non-bereaved cohorts. SBS had the greatest rate of depression post-bereavement (50·96%), followed by UI (38·52%) and SND (33·70%) spouses. When comparing bereavement cohorts, a significant group-by-time interaction (P = 0·047) revealed the rate change for depression was significantly different between suicide and UI-bereaved spouses, with SBS having higher rates of depression before bereavement. SBS had increased rates of any mental disorder both pre (ARR = 1·35, 95% CI = 1·03-1·18, P<·05) and post spousal death (ARR = 1·24, 95% CI = 1·03-1·45, P<·05) when compared to UI spouses signifying pre-existing mental disorders. Post-bereavement, SBS had greater rates of depression only when compared to SND-bereaved spouses (ARR = 1·31, 95% CI = 1·10-1·55, P<·01).

INTERPRETATION

SBS have the greatest rates of depression and any mental disorder before the death of their spouse, suggesting suicide bereavement may be unique. Sudden spousal bereavement is a vulnerable time for mental disorders.

摘要

背景

本研究比较了一组纵向的基于人群的丧偶自杀者和其他突然死亡者的配偶,以确定丧偶自杀者(SBS)是否经历更高的医生诊断精神障碍率。

方法

首先,将丧偶自杀、突然自然死亡(SND)和意外损伤(UI)的已婚者与未丧偶的匹配队列进行比较,以确定丧亲组和未丧偶匹配组之间的精神障碍率是否存在差异。其次,使用逆概率治疗加权和广义估计方程比较 SBS(n=365)、SND 丧偶配偶(n=1000)和 UI 丧偶配偶(n=270),以计算死亡前/后 5 年精神障碍的相对发生率。

结果

所有丧偶队列的精神障碍率均高于未丧偶队列。SBS 丧偶后抑郁的发生率最高(50.96%),其次是 UI(38.52%)和 SND(33.70%)配偶。在比较丧亲组时,显著的组-时间交互作用(P=0.047)表明,自杀和 UI 丧偶配偶的抑郁率变化明显不同,SBS 在丧偶前的抑郁率更高。与 UI 丧偶配偶相比,SBS 无论是在丧偶前(ARR=1.35,95%CI=1.03-1.18,P<0.05)还是在配偶死亡后(ARR=1.24,95%CI=1.03-1.45,P<0.05),都有更高的任何精神障碍发生率,表明存在先前的精神障碍。丧偶后,与 SND 丧偶配偶相比,SBS 只有在抑郁方面的发生率更高(ARR=1.31,95%CI=1.10-1.55,P<0.01)。

解释

SBS 在配偶去世前有最高的抑郁率和任何精神障碍率,这表明丧偶自杀可能是独特的。配偶的突然去世是精神障碍的脆弱时期。

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