Duffy P E, Graf L, Rapport M M
J Neuropathol Exp Neurol. 1977 Jul;36(4):645-52. doi: 10.1097/00005072-197707000-00001.
The immunocytochemical localization of glial fibrillary acidic portein within glioma cell bodies and their processes by the immunoperoxidase method is demonstrated to be of diagnostic value. This method has advantages over "special" stains because it is not so dependent upon color alone, and because it identifies a specific protein in the cells. The immunoperoxidase method using antiserum to glial fibrillary acidic protein is shown to be useful for the differentiation of mixed glial and mesenchymal tumors, and for the diagnosis of tumors in which a glial or mesenchymal cell origin is in doubt.
通过免疫过氧化物酶法对神经胶质瘤细胞体及其突起内的胶质纤维酸性蛋白进行免疫细胞化学定位，已证明具有诊断价值。该方法比“特殊”染色法具有优势，因为它不单纯依赖颜色，而且能识别细胞中的一种特定蛋白质。使用抗胶质纤维酸性蛋白抗血清的免疫过氧化物酶法被证明可用于鉴别混合性胶质和间充质肿瘤，以及诊断胶质或间充质细胞起源存疑的肿瘤。
