Rai Sumit, Sharma Pramod Kumar, Tyagi Nirpex, Agarwal Sugandh
Department of Clinical Microbiology, Super Specialty Paediatric Hospital, Postgraduate Teaching Institute, Noida, Uttar Pradesh, India.
Department of Paediatric Surgery, Super Specialty Paediatric Hospital, Postgraduate Teaching Institute, Noida, Uttar Pradesh, India.
Indian J Med Microbiol. 2020 Apr-Jun;38(2):216-218. doi: 10.4103/ijmm.IJMM_20_250.
Staphylococcus aureus and other Gram negative bacteria produce small colony variants (SCV) which usually emerge after exposure to antimicrobials. They cause repeated infections, treatment failures and often pass unnoticed during cultures due to unusual appearance and incomplete incubation. This infectious disease grand round highlights a similar clinical case with atypical history and appearance of a SCV of S. aureus and why prolonged incubation is necessary for aspirates from patients with recurrent infections like abscesses.
金黄色葡萄球菌和其他革兰氏阴性菌会产生小菌落变异体（SCV），这些变异体通常在接触抗菌药物后出现。它们会导致反复感染、治疗失败，并且由于外观异常和培养不完全，在培养过程中常常未被注意到。本次传染病病例讨论会重点介绍了一个具有非典型病史和金黄色葡萄球菌SCV外观的类似临床病例，以及为什么对于脓肿等反复感染患者的吸出物进行延长培养是必要的。
