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沙库巴曲缬沙坦治疗植入式心脏复律除颤器患者的逆向重构及心律失常负荷降低:病例报告

Reverse remodeling and arrhythmic burden reduction in a patient with an implantable cardioverter defibrillator treated with sacubitril/valsartan: Case report.

作者信息

Corrado Egle, Saladino Antonino, Morgante Giusy, Mignano Antonino, Nugara Cinzia, Novo Giuseppina, Coppola Giuseppe

机构信息

UTIC - Cardiologia Policlinico Universitario Paolo Giaccone Palermo Italy.

出版信息

Clin Case Rep. 2020 Jun 9;8(8):1349-1352. doi: 10.1002/ccr3.2655. eCollection 2020 Aug.

Abstract

Sacubitril/valsartan has been shown to reduce cardiovascular mortality and hospitalizations in patients with HFrEF when compared to enalapril. There are also some evidences of its potential antiarrhythmic effects. We present a report where we found a relation between reverse ventricular remodeling and arrhythmic reduction in a patient treated with sacubitril/valsartan.

摘要

与依那普利相比,沙库巴曲缬沙坦已被证明可降低射血分数降低的心力衰竭(HFrEF)患者的心血管死亡率和住院率。也有一些证据表明其具有潜在的抗心律失常作用。我们报告了一例使用沙库巴曲缬沙坦治疗的患者,发现其逆向心室重构与心律失常减少之间存在关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d7a/7455401/dca7b435bd63/CCR3-8-1349-g001.jpg

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