Nezhat Farr R, Zavala Retes Benjamin, White Michael P, Donovan Virginia, Pejovic Tanja
259 First St, NYU Winthrop Hospital, NYU-Long Island School of Medicine, Mineola, NY 10158, USA.
525 East 68th St, Weill Cornell Medical College of Cornell University, New York, NY 10165, USA.
Gynecol Oncol Rep. 2020 Aug 12;33:100622. doi: 10.1016/j.gore.2020.100622. eCollection 2020 Aug.
•Highly suspicious pelvic mass may require preoperative biopsy for diagnosis.•Neoadjuvant imatinib lowers EGIST tumor burden in extensive disease preoperatively.•EGIST resection aims at complete surgical resection and negative margins.•This case was managed with complete surgical resection and adjuvant imatinib.•Prognostic factors in EGIST are size, mitosis, location and genetic mutations.
•高度可疑的盆腔肿块可能需要术前活检以明确诊断。
•新辅助伊马替尼可降低术前广泛病变的EGIST肿瘤负荷。
•EGIST切除旨在实现完整的手术切除及切缘阴性。
•该病例采用完整手术切除及辅助伊马替尼治疗。
•EGIST的预后因素包括大小、有丝分裂、位置和基因突变。