Kitazaki Yuki, Ueno Asako, Maeda Kenichiro, Asano Rei, Satomi Hiroyuki, Nishio Taro, Nakamoto Yasunari, Hamano Tadanori
Department of Neurology, Fukui-ken Saiseikai Hospital, Fukui, Japan.
Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
eNeurologicalSci. 2020 Aug 14;21:100264. doi: 10.1016/j.ensci.2020.100264. eCollection 2020 Dec.
Severe neurologic complications following epidural and spinal anesthesia rarely occur. Transverse myelitis has been reported as a rare complication of epidural or spinal anesthesia. We report a case of longitudinally extensive transverse myelitis and an isolated pontine lesion, which responded to immunotherapy. The patient was a 31-year-old pregnant woman who underwent elective cesarean section under epidural and spinal anesthesia. Though the insertions of the epidural and spinal catheters were smooth, she experienced back pain and transient hearing loss during epidural anesthesia. Postoperatively, she exhibited severe motor weakness in both lower extremities, neuralgia below the level of Th10 dermatome, and urinary retention. Magnetic resonance imaging showed longitudinally extensive transverse myelitis from T6 to T10 with a ring-shaped enhanced lesion and an isolated pontine lesion. These findings on magnetic resonance imaging were suggestive of autoimmune diseases such as neuromyelitis optica. The patient was diagnosed with an immunoreactive disease triggered by epidural or spinal anesthesia and was administered high-dose methylprednisolone, which led to the improvement in clinical symptoms. Clinicians should be aware of the possibility of the development of longitudinally extensive transverse myelitis and isolated pontine lesions after cesarean section under epidural and spinal anesthesia.
硬膜外麻醉和脊髓麻醉后严重的神经并发症很少发生。横贯性脊髓炎已被报道为硬膜外或脊髓麻醉的一种罕见并发症。我们报告一例纵向广泛横贯性脊髓炎和孤立性脑桥病变的病例,该病例对免疫治疗有反应。患者为一名31岁的孕妇,在硬膜外和脊髓麻醉下接受择期剖宫产。尽管硬膜外导管和脊髓导管的插入过程顺利,但她在硬膜外麻醉期间出现背痛和短暂性听力丧失。术后,她双下肢出现严重运动无力、T10皮节水平以下神经痛和尿潴留。磁共振成像显示从T6到T10的纵向广泛横贯性脊髓炎,伴有环形强化病变和孤立性脑桥病变。磁共振成像的这些发现提示为视神经脊髓炎等自身免疫性疾病。该患者被诊断为由硬膜外或脊髓麻醉引发的免疫反应性疾病,并接受了大剂量甲泼尼龙治疗,临床症状得到改善。临床医生应意识到在硬膜外和脊髓麻醉下剖宫产术后发生纵向广泛横贯性脊髓炎和孤立性脑桥病变的可能性。