From the Departments of Medicine and Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, and the South Carolina Department of Health & Environmental Control, Columbia.
South Med J. 2020 Sep;113(9):415-417. doi: 10.14423/SMJ.0000000000001139.
To evaluate the effect of a 2016 South Carolina payor mandate to query the state prescription drug monitoring program (PDMP) before prescribing controlled substances on the rate of opioid prescribers in South Carolina.
South Carolina PDMP datasets from 2010-2017 were evaluated using interrupted time series regression to compare changes in the rate of opioid prescribers before and after the 2016 mandate. The rate of opioid prescribers was defined as the number of prescribers who prescribed class II to IV opioids on any one prescription in each quarter divided by the total number of South Carolina prescribers who prescribed any one class II to IV medication. The rate of high-dose opioid prescribers was defined as the number of prescribers who prescribed ≥90-morphine milligram equivalent per day on any one prescription in each quarter divided by all of the prescribers who prescribed an opioid analgesic prescription.
The rates of South Carolina opioid prescribers decreased from 75% in 2010 to 60% in 2017, with no significant change in slope ( = 0.24) after the 2016 payor mandates. The rates of South Carolina high-dose opioid prescribers decreased from 40% in 2010 to 32% in 2017, with a significant decrease in slope ( < 0.001) after the payor mandate.
The slope of the South Carolina high-dose opioid prescriber rate significantly decreased after the 2016 South Carolina payor mandate, while the slope of the South Carolina opioid prescriber rate did not. The long-term outcomes related to the change in opioid prescriber rates are unknown and warrant further study.
评估 2016 年南卡罗来纳州支付者要求在开具受控物质之前查询州处方药物监测计划（PDMP）对南卡罗来纳州阿片类药物开方者比例的影响。
使用中断时间序列回归对 2010 年至 2017 年南卡罗来纳州 PDMP 数据集进行评估，以比较 2016 年强制令前后阿片类药物开方者比例的变化。阿片类药物开方者的比例定义为每季度任何一张处方开具 II 类至 IV 类阿片类药物的开方者数量除以开具任何一种 II 类至 IV 类药物的南卡罗来纳州开方者总数。高剂量阿片类药物开方者的比例定义为每季度任何一张处方开具≥90 吗啡毫克当量的开方者数量除以开具阿片类镇痛处方的所有开方者。
南卡罗来纳州阿片类药物开方者的比例从 2010 年的 75%下降到 2017 年的 60%，在 2016 年支付者强制令之后斜率没有明显变化（=0.24）。南卡罗来纳州高剂量阿片类药物开方者的比例从 2010 年的 40%下降到 2017 年的 32%，在支付者强制令之后斜率显著下降（<0.001）。
在 2016 年南卡罗来纳州支付者强制令之后，南卡罗来纳州高剂量阿片类药物开方者的比例斜率显著下降，而南卡罗来纳州阿片类药物开方者的比例斜率没有变化。与阿片类药物开方者比例变化相关的长期结果尚不清楚，需要进一步研究。
