Matsumura Akira, Namikawa Takashi, Kato Minori, Hori Yusuke, Hidaka Noriaki, Nakamura Hiroaki
1Department of Orthopaedic Surgery, Osaka City General Hospital; and.
2Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
J Neurosurg Spine. 2020 Sep 4;34(1):66-72. doi: 10.3171/2020.6.SPINE20670. Print 2021 Jan 1.
The object of this study was to analyze the prevalence of postoperative coronal imbalance (CIB) and related factors in patients with adult lumbar scoliosis.
This was a retrospective single-center study of data from patients with adult spinal deformity (ASD) who had undergone corrective surgery performed by a single surgeon between 2009 and 2017. The inclusion criteria were as follows: 1) age at surgery > 40 years, 2) Cobb angles of the thoracolumbar/lumbar (TL/L) curve > 40°, 3) upper instrumented vertebra of T9 or T10, 4) lowest instrumented vertebra of L5 or the pelvis, and 5) minimum 2-year follow-up period. Radiographic parameters were measured before surgery, 2 weeks after surgery, and at the latest follow-up. Curve flexibility was also assessed using side bending radiographs. Clinical outcomes were evaluated using the 22-Item Scoliosis Research Society Outcomes Questionnaire (SRS-22) and the SF-36. CIB was considered to have occurred if the C7 plumbline was more than 2.5 cm lateral to the central sacral vertical line (i.e., coronal vertical axis [CVA] > 2.5 cm) at the final follow-up. Parameters between the patients with (CIB group) and without (coronal balance [CB] group) CIB were compared, and factors related to CIB were evaluated.
From among 66 consecutively treated ASD patients, a total of 37 patients (mean age at surgery 66.3 years, average follow-up 63 months) met the study inclusion criteria. CIB was found in 6 patients at the final follow-up (16.2%), and the CVA of all patients in the CIB group shifted to the convex side of the TL/L curve. A comparative analysis between the CB and CIB groups, respectively, at the final follow-up indicated the following factors were related to CIB: lumbosacral (LS) curve, 11.0°/16.5° (p = 0.02); LS correction rate (CR), 61%/47% (p = 0.02); and CR ratio (LS vs TL/L), 0.93/0.67 (p = 0.0002). Regarding clinical outcomes, the satisfaction domain of the SRS-22 (CB 4.4 vs CIB 3.5) showed a significant difference between the CIB and CB groups (p = 0.02), and patients in the CB group tended to score better on the pain domain (CB 4.3 vs CIB 3.7), but the difference was not significant (p = 0.06).
Postoperative CIB negatively impacted patients' HRQOL. An imbalanced correction ratio between the TL/L and LS curves may cause postoperative CIB. Therefore, adequate correction of the LS curve may prevent postoperative CIB.
本研究旨在分析成人腰椎侧弯患者术后冠状面失衡(CIB)的发生率及相关因素。
这是一项回顾性单中心研究,收集了2009年至2017年间由同一外科医生进行矫正手术的成人脊柱畸形(ASD)患者的数据。纳入标准如下:1)手术年龄>40岁;2)胸腰段/腰段(TL/L)曲线的Cobb角>40°;3)上固定椎为T9或T10;4)下固定椎为L5或骨盆;5)至少随访2年。在手术前、术后2周及最后一次随访时测量影像学参数。还使用侧弯X线片评估曲线柔韧性。使用22项脊柱侧弯研究学会结局问卷(SRS-22)和SF-36评估临床结局。如果在最后一次随访时C7铅垂线位于骶骨中心垂直线外侧超过2.5 cm(即冠状垂直轴[CVA]>2.5 cm),则认为发生了CIB。比较了发生CIB的患者(CIB组)和未发生CIB的患者(冠状面平衡[CB]组)之间的参数,并评估了与CIB相关的因素。
在66例连续接受治疗的ASD患者中,共有37例患者(手术时平均年龄66.3岁,平均随访63个月)符合研究纳入标准。在最后一次随访时,6例患者出现CIB(16.2%),CIB组所有患者的CVA均向TL/L曲线的凸侧偏移。在最后一次随访时,分别对CB组和CIB组进行的比较分析表明,以下因素与CIB相关:腰骶部(LS)曲线,11.0°/16.5°(p = 0.02);LS矫正率(CR),61%/47%(p = 0.02);以及CR比率(LS与TL/L),0.93/0.67(p = 0.0002)。关于临床结局,SRS-22的满意度领域(CB组为4.4,CIB组为3.5)在CIB组和CB组之间存在显著差异(p = 0.02),CB组患者在疼痛领域的得分往往更高(CB组为4.3,CIB组为3.7),但差异不显著(p = 0.06)。
术后CIB对患者的健康相关生活质量产生负面影响。TL/L和LS曲线之间的矫正率失衡可能导致术后CIB。因此,充分矫正LS曲线可能预防术后CIB。